Evidence map›Paper›PMID 35245932›Full record

ArticleThe Journal of infectious diseases2022

Infection History and Current Coinfection With Schistosoma mansoni Decreases Plasmodium Species Intensities in Preschool Children in Uganda.

Daniel McDowell, Lisa Hurt, Narcis B Kabatereine, John Russell Stothard, Joanne Lello

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Daniel McDowellSchool of Biosciences, Cardiff University, Cardiff, United Kingdom.
Lisa HurtSchool of Medicine, Cardiff University, Cardiff, United Kingdom.
Narcis B KabatereineVector Control Division, Ministry of Health, Kampala, Uganda.
John Russell StothardDepartment of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0002-9370-3420
Joanne LelloSchool of Biosciences, Cardiff University, Cardiff, United Kingdom.
Cardiff University · GBLiverpool School of Tropical Medicine · GBMinistry of Health · UG

Funding

Wellcome Trust
6 · The paper itself

Abstract

Malaria-schistosomiasis coinfections are common in sub-Saharan Africa but studies present equivocal results regarding the interspecific relationships between these parasites. Through mixed-model analyses of a dataset of Ugandan preschool children, we explore how current coinfection and prior infection with either Schistosoma mansoni or Plasmodium species alter subsequent Plasmodium intensity, Plasmodium risk, and S mansoni risk. Coinfection and prior infections with S mansoni were associated with reduced Plasmodium intensity, moderated by prior Plasmodium infections, wealth, and host age. Future work should assess whether these interactions impact host health and parasite control efficacy in this vulnerable age group.

Indexed as

CoinfectionMalariaPlasmodiumSchistosomiasis mansoniAnimalsChild, PreschoolHumansSchistosoma haematobiumSchistosoma mansoniUgandacoinfectionPlasmodium speciespreschool-aged childrenprior infectionsSchistosoma mansoni

Identifiers

PMID35245932
PMCPMC9200150
OpenAlexW4214924847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.