Evidence map›Paper›PMID 35245916›Full record

ArticleJournal of addiction medicine

Assessing the Impact of Prenatal Medication for Opioid Use Disorder on Discharge Home With Parents Among Infants With Neonatal Opioid Withdrawal Syndrome.

Rosalyn Singleton, Sara Rutz, Gretchen Day, Melissa Hammes, Amy Swango Wilson, Mary Herrick, Connie Mazut, Laura Brunner, Jennifer Prince, Christine Desnoyers and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Rosalyn SingletonFrom the Alaska Native Tribal Health Consortium, Anchorage, AK (RS, GD, SW, CM); University of Washington, School of Medicine, Alaska WWAMI, Anchorage, AK (SR); Southcentral Foundation, Anchorage, AK (MH, MH, JS, MH); Fairbanks Memorial Hospital, Fairbanks, AK (LB); Yukon Kuskokwim Health Corporation, Bethel, AK (JP); Yukon Kuskokwim Health Corporation, Bethel, Alaska (CD); Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada (HP); British Columbia Centre for Disease Control, Vancouver, BC, Canada (HP, AS); School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada (AS).
Sara Rutz
Gretchen Day
Melissa Hammes
Amy Swango Wilson
Mary Herrick
Connie Mazut
Laura Brunner
Jennifer Prince
Christine Desnoyers
Jennifer Shaw
Matthew Hirschfeld
Heather Palis
Amanda Slaunwhite
Yukon Kuskokwim Health Corporation · US

Funding

Tracking and Evaluation CoreU54GM115371 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI RASMUS, STACY M., VOYICH, JOVANKA M · 2016 to 2020
$20.9M
Researcher Career Enhancement ProjectS06GM142122 · NIGMS · SOUTHCENTRAL FOUNDATION · PI BEANS, JULIE · 2021 to 2024
$3.9M
Evaluation of a HEPA Filter Pilot Project: Formative Data to Support a Future Indoor Air Quality Bronchiolitis Clinical TrialUG1OD024944 · OD · ALASKA NATIVE TRIBAL HEALTH CONSORTIUM · PI HIRSCHFELD, MATTHEW J, KECK, JAMES W. · 2016 to 2024
$2.3M
Clinical Sites for the IDeA States Pediatric Clinical Trials NetworkUG1HD090875 · NICHD · ALASKA NATIVE TRIBAL HEALTH CONSORTIUM · PI SINGLETON, ROSALYN · 2016 to 2016
$19k
NICHD NIH HHS UG1 HD090875NIGMS NIH HHS S06 GM142122NIGMS NIH HHS U54 GM115371NIH HHS UG1 OD024944
6 · The paper itself

Abstract

objectivesThe number of women with opioid-related diagnoses in the United States has significantly increased in recent decades, resulting in concomitantly higher rates of infants born with neonatal opioid withdrawal syndrome (NOWS). Addressing prenatal opioid exposure is a priority for Alaska health systems. The objectives of this study were to: (1) identify maternal and neonatal factors associated with receipt of Medication for opioid use disorder (MOUD) and (2) determine the impact of prenatal MOUD on discharge to parents among infants with NOWS in 3 Alaska hospitals.

methodsA retrospective chart review using a standard abstraction form was conducted to collect data on neonatal and maternal characteristics, neonatal treatment, and infant discharge disposition for infants with NOWS born at the 3 hospitals between July 2016 and December 2019. A multivariable logistic regression model was used to determine factors associated with discharge to parents.

resultsThere were 10,719 births at the 3 hospitals during the study period, including 193 infants (1.8%) with NOWS. Among the 193 mothers, 91 (47.2%) received MOUD during pregnancy. Among infants with NOWS, 136 (70.5%) were discharged to parents, 51 (26.4%) were discharged to a relative or foster care. Infants were significantly (odds ratio 3.9) more likely to be discharged to parents if the mother had received prenatal MOUD.

conclusionsMOUD among pregnant women with opioid use disorder furthers the goal of keeping families together and is a critical step towards reducing the impact of the ongoing opioid epidemic on Alaska families, communities, and the child welfare system.

Indexed as

Neonatal Abstinence SyndromeOpioid-Related DisordersSubstance Withdrawal SyndromeAnalgesics, OpioidChildFemaleHumansInfantInfant, NewbornParentsPatient DischargePregnancyRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID35245916
PMCPMC9433459
OpenAlexW4220736214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.