Evidence map›Paper›PMID 35245022›Full record

ArticleACS synthetic biology2022

Polymer Encapsulation of Bacterial Biosensors Enables Coculture with Mammalian Cells.

Ignacio Moya-Ramírez, Pavlos Kotidis, Masue Marbiah, Juhyun Kim, Cleo Kontoravdi, Karen Polizzi

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Engineered Bacteria as Living Biosensors in Dermal Tattoos.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  3. Article
  4. A Portable, Encapsulated Microbial Whole-Cell Biosensing System for the Detection of Bioavailable Copper (II) in Soil.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2023
    Article
  5. Biomimetic behaviors in hydrogel artificial cells through embedded organelles.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  6. Engineered Living Hydrogels.Advanced materials (Deerfield Beach, Fla.) · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ignacio Moya-RamírezDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0001-9584-7922
Pavlos KotidisDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.
Masue MarbiahDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0001-8045-4843
Juhyun KimDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.
Cleo KontoravdiDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.
Karen PolizziDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0001-5435-2667
Imperial College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/S006206/1
6 · The paper itself

Abstract

Coexistence of different populations of cells and isolation of tasks can provide enhanced robustness and adaptability or impart new functionalities to a culture. However, generating stable cocultures involving cells with vastly different growth rates can be challenging. To address this, we developed living analytics in a multilayer polymer shell (LAMPS), an encapsulation method that facilitates the coculture of mammalian and bacterial cells. We leverage LAMPS to preprogram a separation of tasks within the coculture: growth and therapeutic protein production by the mammalian cells and l-lactate biosensing by

Indexed as

Biosensing TechniquesPolymersBacteriaCoculture TechniquesEscherichia coliPolymersbacteriabiosensorcoculturehydrogel encapsulationl-lactatemammalian cells

Identifiers

PMID35245022
PMCPMC9007569
OpenAlexW4221012134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.