Evidence map›Paper›PMID 35244930›Full record

ArticleLa Tunisie medicale

The risk of subclinical carotid atherosclerosis in patients with chronic hepatitis C.

Mouna Medhioub, Khaled Bouzaidi, Asma Bachali, Amal Khsiba, Lamine Hamzaoui, Mohamed Moussadek Azouz

Open access · greenAbstract read
In one paragraph

Article in La Tunisie medicale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. La Tunisie medicale · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mouna Medhioub
Khaled Bouzaidi
Asma Bachali
Amal Khsiba
Lamine Hamzaoui
Mohamed Moussadek Azouz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe role of hepatitis C virus in the pathogenesis of atherosclerotic disease has been suggested by several studies.

aimTo assess the association between subclinical carotid atherosclerosis and chronic hepatitis C.

methods40 patients infected with chronic hepatitis C and 40 control cases were evaluated by anthropometric and metabolic measurements. The risk of subclinical atherosclerosis was assessed by ultrasound measurement of carotid intima-media thickness. A high cardiovascular risk atherosclerosis was defined by carotid intima-media thickness > 75th percentile.

resultsThe carotid intima-media thickness and the prevalence of high cardiovascular risk atherosclerosis were significantly higher in the group infected with hepatitis C compared to the control group (0.68 VS 0.60, p=0.02) and (82.5% vs. 40%; 0.001) respectively. In multivariate studies, activity ≥ A2 and age> 40 years were the independent factors associated with the carotid intima-media thickness and hepatitis C was the only independent factor associated with high cardiovascular risk atherosclerosis (OR=4.81 CI at 95%: 1.6-14.42).

conclusionsIn our study, chronic hepatitis C was associated with a high risk of carotid atherosclerosis.

Indexed as

AtherosclerosisCarotid Artery DiseasesHepatitis C, ChronicAdultCarotid Intima-Media ThicknessHumansRisk Factors

Identifiers

PMID35244930
PMCPMC8734473
OpenAlexW4287544343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.