Evidence map›Paper›PMID 35244778›Full record

ArticleArchives of microbiology2022

Multidrug-resistant Klebsiella pneumoniae: a retrospective study in Manaus, Brazil.

Rafael Nakamura-Silva, Louise Cerdeira, Mariana Oliveira-Silva, Karen Regina Carim da Costa, Elder Sano, Bruna Fuga, Quézia Moura, Fernanda Esposito, Nilton Lincopan, Kelly Wyres and 1 more

Abstract read
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Epidemiological features of hypermucoviscousFrontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Genetic diversity, drug resistance, and biofilm formation in Klebsiella pneumoniae associated with nosocomial infection in Pelotas, RS, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. High-risk clones of carbapenem resistant Klebsiella pneumoniae recovered from pediatric patients in Southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Genomics ofMicroorganisms · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rafael Nakamura-Silva *Postgraduate Program in Environmental Technology, Universidade de Ribeirão Preto, UNAERP, Bloco J, Laboratório 1. Av. Costábile Romano, 2201 Ribeirânia, Ribeirão Preto, São Paulo, 14096-900, Brazil.
Louise Cerdeira *Department of Infectious Diseases, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Mariana Oliveira-SilvaPostgraduate Program in Environmental Technology, Universidade de Ribeirão Preto, UNAERP, Bloco J, Laboratório 1. Av. Costábile Romano, 2201 Ribeirânia, Ribeirão Preto, São Paulo, 14096-900, Brazil.
Karen Regina Carim da CostaSchool of Pharmaceutical Sciences, Universidade Federal do Amazonas, Manaus, Amazonas, Brazil.
Elder SanoInstitute of Biomedical Sciences, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Bruna FugaInstitute of Biomedical Sciences, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Quézia MouraFederal Institute of Education, Science and Technology of Espírito Santo, Vila Velha, Espírito Santo, Brazil.
Fernanda EspositoOne Health Brazilian Resistance Project (OneBR), São Paulo, São Paulo, Brazil.
Nilton LincopanInstitute of Biomedical Sciences, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Kelly WyresDepartment of Infectious Diseases, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
André Pitondo-SilvaPostgraduate Program in Environmental Technology, Universidade de Ribeirão Preto, UNAERP, Bloco J, Laboratório 1. Av. Costábile Romano, 2201 Ribeirânia, Ribeirão Preto, São Paulo, 14096-900, Brazil. andre@pitondo.com.br.ORCID http://orcid.org/0000-0003-0098-9667

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/22581-5
6 · The paper itself

Abstract

Klebsiella pneumoniae is an opportunistic pathogen that can cause several infections, mainly in hospitalised or immunocompromised individuals. The spread of K. pneumoniae emerging virulent and multidrug-resistant clones is a worldwide concern and its identification is crucial to control these strains especially in hospitals. This article reports data related to multi-resistant K. pneumoniae strains, isolated from inpatients in the city of Manaus, Brazil, harbouring virulence and antimicrobial-resistance genes, including high-risk international clones belonging to clonal group (CG) 258. Twenty-one strains isolated from different patients admitted to four hospitals in the city of Manaus, located in the state of Amazonas, Northern Brazil (Amazon Rainforest region) were evaluated. The majority of strains (61.9% n = 13) were classified as multidrug-resistant (MDR), and five strains (23.8%) as extensively drug-resistant (XDR). Several virulence and antimicrobial-resistance genes were found among the strains and eight strains (38.1%) presented the hyper-mucoviscous phenotype. MLST analysis demonstrated a great diversity of STs among the strains, totaling 12 different STs (ST11, ST23, ST198, ST277, ST307, ST340, ST378, ST462, ST502, ST3991, ST3993 and ST5209). Three of these (ST11, ST23 and ST340) belong to CG258.

Indexed as

Klebsiella InfectionsKlebsiella pneumoniaeAnti-Bacterial Agentsbeta-LactamasesBrazilDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMultilocus Sequence TypingRetrospective StudiesAnti-Bacterial Agentsbeta-LactamasesCG258HypermucoviscousKlebsiella pneumoniaeResistomeVirulomeWGS

Identifiers

PMID35244778
PMCPMC8894834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.