Evidence map›Paper›PMID 35244741›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Physical isolation and mental health among older US adults during the COVID-19 pandemic: longitudinal findings from the COVID-19 Coping Study.

Carly A Joseph, Brendan Q O'Shea, Marisa R Eastman, Jessica M Finlay, Lindsay C Kobayashi

Open access · bronzeAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Subjective Stress Appraisals Over Time: the Evolving Structure of the COVID-19 Stressor Scale.Prevention science : the official journal of the Society for Prevention Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carly A JosephDepartment of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, SPH I, Ann Arbor, MI, 48109, USA.
Brendan Q O'SheaDepartment of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, SPH I, Ann Arbor, MI, 48109, USA.
Marisa R EastmanDepartment of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, SPH I, Ann Arbor, MI, 48109, USA.
Jessica M FinlaySurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Lindsay C KobayashiDepartment of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, SPH I, Ann Arbor, MI, 48109, USA. lkob@umich.edu.ORCID http://orcid.org/0000-0003-2725-3107
University of Michigan · US

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
NIA NIH HHS P30 AG012846NIA NIH HHS P30AG012846NIA NIH HHS P30 AG024824
6 · The paper itself

Abstract

purposeWe investigated the relationships between physical isolation at home during the period when many US states had shelter-in-place orders and subsequent longitudinal trajectories of depression, anxiety, and loneliness in older adults over a 6 month follow-up.

methodsData were from monthly online questionnaires with US adults aged ≥ 55 in the nation-wide COVID-19 Coping Study (April through October 2020, N = 3978). Physical isolation was defined as not leaving home except for essential purposes (0, 1-3, 4-6, and 7 days in the past week), measured at baseline (April-May). Outcomes were depressive symptoms (8-item Center for Epidemiological Studies Depression Scale), anxiety symptoms (5-item Beck Anxiety Inventory), and loneliness (3-item UCLA loneliness scale), measured monthly (April-October). Multivariable, population- and attrition-weighted linear mixed-effects models assessed the relationships between baseline physical isolation with mental health symptoms at baseline and over time.

resultsPhysical isolation (7 days versus 0 days in the past week) was associated with elevated depressive symptoms (adjusted β = 0.85; 95% CI 0.10-1.60), anxiety symptoms (adjusted β = 1.22; 95% CI 0.45-1.98), and loneliness (adjusted β = 1.06; 95% CI 0.51-1.61) at baseline, but not with meaningful rate of change in these mental health outcomes over time. The symptom burden of each mental health outcome increased with increasing past-week frequency of physical isolation.

conclusionDuring the early COVID-19 pandemic, physical isolation was associated with elevated depressive symptoms, anxiety symptoms, and loneliness, which persisted over time. These findings highlight the unique and persistent mental health risks of physical isolation at home under pandemic control measures.

Indexed as

COVID-19Adaptation, PsychologicalAdultAgedAnxietyDepressionHumansLonelinessMental HealthMiddle AgedPandemicsAgingIsolationLonelinessMental health

Identifiers

PMID35244741
PMCPMC8895362
OpenAlexW4214812632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.