Evidence map›Paper›PMID 35244539›Full record

ArticleeLife2022

Structural dynamics determine voltage and pH gating in human voltage-gated proton channel.

Shuo Han, Sophia Peng, Joshua Vance, Kimberly Tran, Nhu Do, Nauy Bui, Zhenhua Gui, Shizhen Wang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Transcendent Aspects of Proton Channels.Annual review of physiology · 2024
    Review
  8. Article
  9. Review
  10. Cholesterol inhibits human voltage-gated proton channel hHv1.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shuo HanDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.ORCID 0000-0003-0358-1851
Sophia PengDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.ORCID 0000-0002-7434-5445
Joshua VanceDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.
Kimberly TranDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.
Nhu DoDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.
Nauy BuiDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.
Zhenhua GuiDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.
Shizhen WangDepartment of Cell Biology and Biophysics, School of Biological and Chemical Sciences, University of Missouri-Kansas City, Kansas City, United States.ORCID 0000-0003-1065-4756
University of Missouri–Kansas City · US

Funding

Structural dynamics underlying voltage and pH gating of the human proton channelR15GM137315 · NIGMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI WANG, SHIZHEN · 2020 to 2022
$467k
NIGMS NIH HHS R15 GM137315
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ion Channel GatingProtonsHumansIon ChannelsKineticsProtein Structure, SecondaryIon ChannelsProtonsE. colihumanion channelmembrane proteinmolecular biophysicsproton channelsingle-molecule FRETstructural biologystructural dynamicsvoltage gating

Identifiers

PMID35244539
PMCPMC8926398
OpenAlexW4220715775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.