Evidence map›Paper›PMID 35244369›Full record

ArticleBrazilian journal of cardiovascular surgery2022

C-Reactive Protein to Albumin Ratio as A Novel Inflammatory-Based Marker for 30-Day Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement.

Fahrettin Katkat, Muhsin Kalyoncuoglu, Sevgi Ozcan, Sevil Tugrul, Hanife Abanus, Orhan Ince, Mehmet Balli, Irfan Sahin, Ertugrul Okuyan

Abstract read
In one paragraph

Article in Brazilian journal of cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Association of the CALLY Index With 30-Day Outcomes After Transcatheter Aortic Valve Replacement.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
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  10. C-reactive protein-to-albumin ratio is associated with mortality after transcatheter tricuspid valve repair.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fahrettin KatkatCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Muhsin KalyoncuogluCardiology Department, Haseki Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Sevgi OzcanCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Sevil TugrulCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Hanife AbanusCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Orhan InceCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Mehmet BalliCardiology Department, Mersin Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Irfan SahinCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Ertugrul OkuyanCardiology Department, Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate whether C-reactive protein to albumin ratio (CAR) predicts the early and late mortality in patients undergoing transcatheter aortic valve replacement (TAVR).

methodsThis study was retrospectively designed and includes 170 TAVR patients with a mean age of 78.4±7.1 years. Patients were divided into 2 groups as those who died and those who survived, taking into account the follow-up period. Complete blood count, serum CRP and serum albumin were obtained on admission. The CAR value of all patients was calculated and the relationship of CAR with early (≤30 days) and late mortality (>30 days) was evaluated.

resultsThe median follow-up period was 19 [7-31] months (maximum 66 months). Early mortality was observed in 20 (11.8%) patients, whereas late mortality was observed in 39 (22.9%) patients, most of them male (61.1%, P=0.04). Non-survivors had greater CAR value, higher baseline serum CRP level and lower baseline albumin level than survivors (P<0.01, for all parameters). According to multivariate analysis models, CAR (HR: 1.020, P<0.01) and TVAR score (HR: 1.294, P<0.01) were found to be independent predictors of early mortality while CRP and albumin were not. The area under the curve (AUC) for CAR was 0.73 with a P <0.01. A CAR >15.6 predicted the early mortality with 80% sensitivity and 57% specificity.

conclusionThe novel inflammatory marker CAR can be used as a reliable marker in predicting 30-day mortality in patients undergoing TAVR.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveBiomarkersC-Reactive ProteinFemaleHumansMaleRetrospective StudiesRisk FactorsTreatment OutcomeBiomarkersC-Reactive ProteinAortic StenosisC-Reactive ProteinMortalitySerum AlbuminTranscatheter Aortic Valve Replacement

Identifiers

PMID35244369
PMCPMC9162408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.