Evidence map›Paper›PMID 35244231›Full record

ArticleVeterinary clinical pathology2022

Comparison of three hematocrit measurement methods in the southern white rhinoceros (Ceratotherium simum simum).

Christof Steyrer, Friederike Pohlin, Leith C R Meyer, Peter Buss, Emma H Hooijberg

Open access · hybridAbstract read
In one paragraph

Article in Veterinary clinical pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Christof Steyrer *Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-0029-1242
Friederike Pohlin *Research Institute of Wildlife Ecology, Department of Interdisciplinary Life Sciences, University of Veterinary Medicine Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-4236-5847
Leith C R MeyerCentre for Veterinary Wildlife Studies, Faculty of Veterinary Science, Onderstepoort Campus, University of Pretoria, Pretoria, Gauteng, South Africa.ORCID https://orcid.org/0000-0002-5122-2469
Peter BussCentre for Veterinary Wildlife Studies, Faculty of Veterinary Science, Onderstepoort Campus, University of Pretoria, Pretoria, Gauteng, South Africa.
Emma H HooijbergCentre for Veterinary Wildlife Studies, Faculty of Veterinary Science, Onderstepoort Campus, University of Pretoria, Pretoria, Gauteng, South Africa.ORCID https://orcid.org/0000-0002-4367-799X
Onderstepoort Veterinary Academic Hospital · ZAUniversity of Veterinary Medicine Vienna · ATSouth African National Parks · ZA

Funding

International Rhino FoundationSouth African National ParksUniversity of PretoriaVeterinary Wildlife Services, Kruger National ParkZebra Foundation for Veterinary Zoological Education
6 · The paper itself

Abstract

backgroundHematocrit (HCT) determination is an integral part of health and disease assessments in captive and wild white rhinoceroses. Several affordable automated hematology analyzers have been developed for in-clinic and field use and have the advantage of being able to measure a large number of additional measurands. However, the accuracy of these analyzers for rhinoceros HCT measurements has not yet been investigated.

objectivesWe aimed to compare the HCT results generated by the EPOC portable analyzer system and the Abaxis VetScan HM5 with the gold standard of a manual packed cell volume (PCV) measured using the microhematocrit method.

methodsHematocrits were measured with the EPOC and the Abaxis VetScan HM5 (bovine setting) and compared with the PCVs of 69 white rhinoceros whole blood samples. Results were compared using Bland-Altman difference plots and Passing-Bablok regression analysis. A total allowable analytical error of 10% was set as the performance goal.

resultsA significant positive bias, with a mean of 7.7% for the EPOC and 17.9% for the Abaxis, was found compared with the manual PCV method.

conclusionsThe allowable error goal of 10% was not exceeded with the EPOC analyzer. Although not analytically equivalent to the gold standard, the EPOC results could therefore be used as approximations in critical situations where manual measurements cannot be performed. The Abaxis exceeded this allowable error and overestimated HCTs in rhinoceroses. Therefore, method-specific reference intervals should be used.

Indexed as

PerissodactylaAnimalsCattleHematocritReference ValuesAbaxis HM5EPOCmethod comparisonpacked cell volumepoint-of-care

Identifiers

PMID35244231
PMCPMC9310865
OpenAlexW4214808296

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.