Evidence map›Paper›PMID 35244137›Full record

ArticleGenetics and molecular biology2022

Genomic analysis of Enterococcus durans LAB18S, a potential probiotic strain isolated from cheese.

Carolina Baldisserotto Comerlato, Janira Prichula, Franciele Maboni Siqueira, Ana Carolina Ritter, Ana Paula Muterle Varela, Fabiana Quoos Mayer, Adriano Brandelli

Open access · goldAbstract read
In one paragraph

Article in Genetics and molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Frontiers in microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Genomic analysis ofMolecular biology research communications · 2022
    Article
  9. Frontiers in veterinary science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Carolina Baldisserotto ComerlatoUniversidade Federal do Rio Grande do Sul, Departamento de Ciência de Alimentos, Laboratório de Bioquímica e Microbiologia Aplicada, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0003-3585-8624
Janira PrichulaUniversidade Federal de Ciências da Saúde de Porto Alegre, Laboratório de cocos Gram-positivos, Porto Alegre, RS, Brazil.
Franciele Maboni SiqueiraUniversidade Federal do Rio Grande do Sul, Departamento de Patologia Clínica Veterinária, Laboratório de Bacteriologia Clínica, Porto Alegre, RS, Brazil.
Ana Carolina RitterUniversidade Federal do Rio Grande do Sul, Departamento de Ciência de Alimentos, Laboratório de Bioquímica e Microbiologia Aplicada, Porto Alegre, RS, Brazil.
Ana Paula Muterle VarelaSecretaria da Agricultura Pecuária e Irrigação do RS, Departamento de Diagnóstico e Pesquisa Agropecuária, Laboratório de Biologia Molecular, Eldorado do Sul, RS, Brazil.
Fabiana Quoos MayerSecretaria da Agricultura Pecuária e Irrigação do RS, Departamento de Diagnóstico e Pesquisa Agropecuária, Laboratório de Biologia Molecular, Eldorado do Sul, RS, Brazil.
Adriano BrandelliUniversidade Federal do Rio Grande do Sul, Departamento de Ciência de Alimentos, Laboratório de Bioquímica e Microbiologia Aplicada, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0002-9307-6471
Universidade Federal do Rio Grande do Sul · BRSecretaria de Agricultura e Abastecimento · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota exerts a fundamental role in human health and increased evidence supports the beneficial role of probiotic microorganisms in the maintenance of intestinal health. Enterococcus durans LAB18S was previously isolated from soft cheese and showed some desirable in vitro probiotic properties, for that reason its genome was sequenced and evaluated for genes that can be relevant for probiotic activity and are involved in selenium metabolism. Genome sequencing was performed using the Illumina MiSeq System. A variety of genes potentially associated with probiotic properties, including adhesion capability, viability at low pH, bile salt resistance, antimicrobial activity, and utilization of prebiotic fructooligosaccharides (FOS) were identified. The strain showed tolerance to acid pH and bile salts, exhibited antimicrobial activity and thrived on prebiotic oligosaccharides. Six genes involved in selenium metabolism were predicted. Analysis of the SECIS element showed twelve known selenoprotein candidates. E. durans LAB18S was the only food isolate showing absence of plasmids, virulence and antimicrobial resistance genes, when compared with other 30 E. durans genomes. The results of this study provide evidence supporting the potential of E. durans LAB18S as alternative for probiotic formulations.

Identifiers

PMID35244137
PMCPMC8894896
OpenAlexW4214498704

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.