Evidence map›Paper›PMID 35244056›Full record

ArticleMedicine2022

Traditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis.

Xiang Feng, Keshang Li, Quanrui Jiang, Yuxing Zhang, Zhichao Gong, Hui Zhi, Jun Yu, Wu Li, Jiangshan Li

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xiang FengSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.ORCID 0000-0002-3591-2435
Keshang LiCollege of Acupuncture and Orthopedics, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Quanrui JiangSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Yuxing ZhangThe First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Zhichao GongSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Hui ZhiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Jun YuSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Wu LiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Jiangshan LiSchool of Acupuncture-Moxibustion and Tuina, Hunan University of Chinese Medicine, Changsha, Hunan, China.ORCID 0000-0001-8377-0497
Hunan University of Traditional Chinese Medicine · CNFirst Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNHubei University of Chinese Medicine · CN

Funding

Research and Innovation Project for Graduate Students in Hunan Province CX2018B487Research and Innovation Project for Graduate Students of Hunan University of Chinese Medicine 2021CX15Science and Technology Bureau, Changsha kq1901093The Research and Development Program in Key Areas of Hunan Province 2019SK2081
6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication, social interaction, and restrictive or repetitive behaviors. Traditional Chinese medicine (TCM) has been used in the clinical management of ASD, especially in mainland China, where studies have shown promising efficacy. However, this remains to be further explored and clarified. Therefore, the purpose of this study was to evaluate the effectiveness and safety of conventional treatment-based TCM interventions for ASD.

methodThe study will be conducted from January 2022, and the following electronic databases will be searched: China Biological Medicine Database, Chinese Scientific Journals Database, Wan Fang database, and China National Knowledge Infrastructure, the Cochrane Library, Web of Science, PubMed, and EMBASE Database. Only randomized controlled trials of TCM interventions for ASD will be included. The Autism Diagnostic Observation Scale, Autism Diagnostic Interview-Revised, and Childhood Autism Rating Scale will be the primary outcome indicators. The methodological quality of this Bayesian-based network meta-analysis will be performed using the "Risk of Bias" tool. Stata 14.0 and WinBUGS 1.4.3 will be used to analyze the data. In addition, assessment of heterogeneity, inconsistency, subgroups, sensitivity, and publication bias will be conducted using the Cochrane Collaboration's tools.

resultsThe results of this study will be submitted to a peer-reviewed journal for publication.

conclusionThis study will help patients recover better, provide clinical evidence for practitioners, and promote the use of TCM in ASD interventions.

Indexed as

Autism Spectrum DisorderBayes TheoremChildHumansMedicine, Chinese TraditionalNetwork Meta-Analysis as TopicResearch DesignSystematic Reviews as TopicTreatment Outcome

Identifiers

PMID35244056
PMCPMC8896422
OpenAlexW4214938233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.