Evidence map›Paper›PMID 35243916›Full record

ReviewJournal of evidence-based integrative medicine

Promoting Plant-Based Therapies for Chronic Kidney Disease.

Muhammad Ali Khan, Andrew J Kassianos, Wendy E Hoy, Ahm Khurshid Alam, Helen G Healy, Glenda C Gobe

Open access · goldAbstract readReview
In one paragraph

Review in Journal of evidence-based integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Metabolic and Antioxidant Modulation byInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Review
  7. Nephroprotective Effect ofInternational journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Renoprotective Effect ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Muhammad Ali KhanNHMRC CKD CRE (CKD.QLD), Univ of Queensland, Brisbane, Australia.ORCID 0000-0002-6980-6112
Andrew J KassianosConjoint Internal Medicine Laboratory, Chemical Pathology, Pathology Queensland, Brisbane, Queensland, Australia.
Wendy E HoyNHMRC CKD CRE (CKD.QLD), Univ of Queensland, Brisbane, Australia.
Ahm Khurshid AlamDepartment of Pharmacy, Univ of Rajshahi, Rajshahi-6205, Bangladesh.
Helen G HealyNHMRC CKD CRE (CKD.QLD), Univ of Queensland, Brisbane, Australia.
Glenda C GobeNHMRC CKD CRE (CKD.QLD), Univ of Queensland, Brisbane, Australia.
Queensland Health · AUThe University of Queensland · AUTranslational Research Institute · AUUniversity of Rajshahi · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is debilitating, increasing in incidence worldwide, and a financial and social burden on health systems. Kidney failure, the final stage of CKD, is life-threatening if untreated with kidney replacement therapies. Current therapies using commercially-available drugs, such as angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and calcium channel blockers, generally only delay the progression of CKD. This review article focuses on effective alternative therapies to improve the prevention and treatment of CKD, using plants or plant extracts. Three mechanistic processes that are well-documented in CKD pathogenesis are inflammation, fibrosis, and oxidative stress. Many plants and their extracts are already known to ameliorate kidney dysfunction through antioxidant action, with subsequent benefits on inflammation and fibrosis.

Indexed as

Renal Insufficiency, ChronicAngiotensin-Converting Enzyme InhibitorsFemaleFibrosisHumansInflammationMalePlant ExtractsAngiotensin-Converting Enzyme InhibitorsPlant Extractschronic kidney diseaseherbal medicineinflammationoxidative stresspathologyplant-based therapies

Identifiers

PMID35243916
PMCPMC8902019
OpenAlexW4214933916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.