ArticlePolish archives of internal medicine2022
Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment.
Article in Polish archives of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
127 citing papers in PubMed, 2 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- The prevalence of positive thyroid autoantibodies in patients with subacute thyroiditis: a systematic review and meta-analysis.Endocrine · 2024Pooled it
- Effects of different supplements on Hashimoto's thyroiditis: a systematic review and network meta-analysis.Frontiers in endocrinology · 2024Pooled it
- The effect of photobiomodulation therapy on fatigue and behavioural status in patients with Hashimoto's thyroiditis.Lasers in medical science · 2026Trial
- Trial
- Ultrasound Radiomics for Hashimoto's Thyroiditis: State of the Art and Future Perspectives.Journal of clinical ultrasound : JCU · 2026Review
- Variable intensity interval training improves cardiorespiratory fitness and quality of life across Hashimoto's stages and lowers TSH in subclinical patients: a 12-week supervised study.European journal of applied physiology · 2026Article
- Association Between Dietary Anthocyanidin Intake and Thyroid Autoimmunity: A Cross-Sectional Study From NHANES (2007-2010).Health science reports · 2026Article
- Systemic inflammatory indices and the FT4/TSH ratio in Hashimoto's thyroiditis: predictive and prognostic implications.Irish journal of medical science · 2026Article
- Review
- When Medical Management Is Not Enough: A Case Report of Progressive Thyromegaly Secondary to Hashimoto Thyroiditis.Cureus · 2026Article
- Clinical and Biochemical Predictors of Thyroid Autoantibody Levels in Hashimoto's Thyroiditis.Cureus · 2026Article
- Article
- Artificial intelligence-based ultrasound diagnosis of Hashimoto's thyroiditis: a systematic review and meta-analysis.Thyroid research · 2026Review
- Association between long-term exposure to environmental coarse particulate matter and the prevalence of thyroid disorders: a cross-sectional study in China.Journal of endocrinological investigation · 2026Article
- Mechanism of Buzhong Yiqi decoction for Hashimoto's thyroiditis: insights from gut microbiota and metabolomics.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Thyroid nodule and autoimmune thyroid disease frequency in adults with inborn errors of immunity: a case-control study.BMC immunology · 2026Article
- Immunonutritional Indices, Inflammatory Markers, and Thyroid-Related Parameters in Adults with Hashimoto's Thyroiditis.Nutrients · 2026Article
- Vascularity assessment in Hashimoto's thyroiditis: a prospective comparative study with power Doppler and superb microvascular imaging.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- Radiomics-Based machine learning for preoperative prediction of Large-Number central lymph node metastasis in papillary thyroid carcinoma.Endocrine · 2026Article
- Hypoxia-Inducible Factor 1-α in Autoimmune Diseases-Insights from the Paradigm of Hashimoto's Thyroiditis: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
67 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Hashimoto thyroiditis (HT) is a common autoimmune disorder, affecting women 7-10 times more often than men, that develops because of genetic susceptibility, Xchromosome inactivation patterns modulated by environmental factors as well as microbiome composition, and leads to an imbalance in self‑tolerance mechanisms. The consequential thyroid infiltration by lymphocytes, potentiated by antibody‑mediated autoimmune response through the antibodies against thyroid peroxidase (TPOAbs), leads to a destruction of thyrocytes. The presence of TPOAbs is associated with a 2 to 4‑fold increase in the risk of recurrent miscarriages and preterm birth in pregnant women. The clinical presentation of HT includes: (A) thyrotoxicosis, when stored thyroid hormones are released to circulation from destroyed thyroid follicles; (B) euthyroidism, when preserved thyroid tissue compensates for destroyed thyrocytes; and (C) hypothyroidism, when thyroid hormone production by the affected thyroid gland is insufficient. The management of Hashitoxicosis is based on symptoms control usually with β‑blockers, euthyroidism requires periodical thyroid stimulating hormone measurements to assess for progression to hypothyroidism, and hypothyroidism is treated with thyroid hormone replacement therapy. The dose of levothyroxine (LT4) used for treatment is based on the degree of preserved thyroid functionality and lean body mass, and usually ranges from 1.4 to 1.8 mcg/kg/day. There is insufficient evidence to recommend for or against therapy with triiodothyronine (T3), apart from in pregnancy when only levothyroxine is indicated, as T3 does not sufficiently cross fetal blood‑brain barrier. HT is associated with 1.6 times higher risk of papillary thyroid cancer and 60 times higher risk of thyroid lymphoma than in general the population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.