SynthesisHIV medicine2022
Comorbidities in women living with HIV: A systematic review.
Synthesis in HIV medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- HIV and cardiovascular diseases: a systematic review and comparative risk assessment study.BMJ global health · 2026Pooled it
- Comorbidities in women living with HIV: A systematic review.HIV medicine · 2022Pooled it
- Need for Medication Review and Deprescribing in People Living with HIV: A Longitudinal Observational Study.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Years gained, health lost? A population-based cohort study of sex differences in healthy life expectancy among people living with HIV.BMJ open · 2026Article
- Navigating the Data Gaps of Ageing Among Women Living With HIV.Journal of the International AIDS Society · 2026Article
- Article
- CD4/CD8 Ratio Increase in Female Living with HIV Switching to Cabotegravir-Rilpivirine: A Real-Life 24 Weeks Evaluation.Pathogens (Basel, Switzerland) · 2025Article
- Biological sex and age influence GS-9620 activity ex vivo.JCI insight · 2025Article
- Burden of Chronic Health Conditions Among People With HIV and Common Non-AIDS-Defining Cancers.Journal of the National Comprehensive Cancer Network : JNCCN · 2025Article
- Poorer Longitudinal Growth Among HIV Exposed Compared With Unexposed Infants in Kenya.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- Review
- Research-based narrative videos to reduce stigma: insights from older women living with HIV.Frontiers in public health · 2025Article
- Article
- Knowledge, attitudes, and barriers: Palliative Care services for women with HIV in resource-limited settings.BMC palliative care · 2024Article
- CD14+CD16+ monocyte transmigration across the blood-brain barrier is associated with HIV-NCI despite viral suppression.JCI insight · 2024Article
- HIV-1 latency reversal and immune enhancing activity of IL-15 is not influenced by sex hormones.JCI insight · 2024Article
- Associations of Early Prolonged Secondary Amenorrhea in Women With and Without HIV.Open forum infectious diseases · 2024Article
- Clinical characteristics of women with HIV in the RESPOND cohort: A descriptive analysis and comparison to men.HIV medicine · 2024Article
- Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.JCI insight · 2024Article
- "As I Grew Older, My Life Got Better": Conceptions of Successful Aging among Older Women Living with or at Risk of HIV.AIDS and behavior · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesEffective antiretroviral therapy (ART) has improved the life expectancy of women living with HIV (WLWH). This population is now experiencing age-related comorbidities. This systematic review presents the current understanding of the prevalence and impact of comorbidities in WLWH in the modern ART era.
methodsMEDLINE and Embase were searched for studies (1 January 2010 to 1 September 2020) reporting the prevalence of cardiovascular, bone, renal and neurocognitive disease in WLWH aged > 18 years. Studies were included if at least 100 participants (or > 50%) were female and data analysis included prevalence by sex.
resultsIn all, 3050 articles were identified and screened; 153 full-text articles were assessed for eligibility and 38 were included in the final review. Significant gaps in the literature were identified, notably a lack of data on WLWH aged > 50 years. The data suggest a high burden of cardiovascular, bone, renal and neurocognitive disease in WLWH compared with HIV negative women. Traditional risk factors, such as hypertension, diabetes and dyslipidaemia, were common and often poorly managed. Generalizability of the results was limited, as many studies were conducted in the USA. Comparisons between WLWH and men with HIV were limited by marked differences in demographic and socioeconomic factors.
conclusionsWomen living with HIV experience a high burden of comorbid disease. Traditional risk factors are common and often poorly managed. This review also highlights the magnitude of differences between women and men living with HIV beyond the pathophysiological. Future research must unpick the complex drivers of morbidity in WLWH, to improve the holistic management of this population.
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Registered trials
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