Evidence map›Paper›PMID 35243741›Full record

ArticleDiabetes, obesity & metabolism2022

Type 2 diabetes pharmacotherapy trends in high-risk subgroups.

Jay Bae, Dongju Liu, Chanadda Chinthammit, Zbigniew Kadziola, Kristina Boye, Kieren Mather

Open access · hybridAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jay BaeEli Lilly and Company, Indianapolis, Indiana, USA.ORCID 0000-0002-2322-1450
Dongju LiuEli Lilly and Company, Indianapolis, Indiana, USA.
Chanadda ChinthammitEli Lilly and Company, Indianapolis, Indiana, USA.
Zbigniew KadziolaEli Lilly and Company, Indianapolis, Indiana, USA.
Kristina BoyeEli Lilly and Company, Indianapolis, Indiana, USA.
Kieren MatherEli Lilly and Company, Indianapolis, Indiana, USA.
Eli Lilly (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medication use trends among patients with type 2 diabetes from 2015 to 2019 were investigated in relation to the clinical group-specific recommendations from the 2018 American Diabetes Association (ADA)/European Association for the Study of Diabetes (EASD) consensus report. Data were drawn from a large health insurance claims database representing Commercial (total patient-year count: 2,379,704) and Medicare (total patient-year count: 845,823) insurance programmes (IBM® MarketScan®). The utilization of sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists increased over time but was lower in the Medicare cohort in every year evaluated. Patients diagnosed with obesity received recommended therapies at higher rates than those without obesity. Differences were more modest between those with versus without atherosclerotic cardiovascular disease (ASCVD) or chronic kidney disease, with greater treatment adoption in those without ASCVD in the Medicare cohort. Utilization of recommended treatments was paradoxically lower in those with versus without heart failure, and worse in the Medicare than in the Commercial cohort. Utilization of sulphonylureas was not different in those with versus without severe hypoglycaemia history. In conclusion, utilization of therapies recommended in the guidelines is increasing overall, which is not preferentially guided by ADA/EASD-defined clinical groups, and there exists a persistent gap in utilization between Commercial and Medicare populations.

Indexed as

AtherosclerosisDiabetes Mellitus, Type 2Sodium-Glucose Transporter 2 InhibitorsAgedFemaleHumansHypoglycemic AgentsMaleMedicareObesityUnited StatesHypoglycemic AgentsSodium-Glucose Transporter 2 Inhibitorsobservational studytype 2 diabetes

Identifiers

PMID35243741
PMCPMC9314938
OpenAlexW4214930408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.