Evidence map›Paper›PMID 35243586›Full record

ArticleAntonie van Leeuwenhoek2022

Whole genome sequencing of the halophilic Halomonas qaidamensis XH36, a novel species strain with high ectoine production.

Tiantian Zhang, Tianqi Cui, Yaning Cao, Yongzhen Li, Fenghui Li, Derui Zhu, Jiangwa Xing

Abstract read
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In one paragraph

Article in Antonie van Leeuwenhoek, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tiantian ZhangResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Tianqi CuiResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Yaning CaoResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Yongzhen LiResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Fenghui LiResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Derui ZhuResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China.
Jiangwa XingResearch Centre of Basic Medical Sciences, Medical College, Qinghai University, Xining, 810016, China. xingjiangwa@qhu.edu.cn.ORCID http://orcid.org/0000-0002-8459-6889
Qinghai University · CN

Funding

National Natural Science Foundation of China (21967018)National Natural Science Foundation of China (31860030)Natural Science Foundation of Qinghai (2018-ZJ-930Q)
6 · The paper itself

Abstract

Here, we report the whole genome of a novel halophilic Halomonas species strain XH36 with high ectoine production potential. The genome was 3,818,310 bp in size with a GC content of 51.97%, and contained 3533 genes, 61 tRNAs and 18 rRNAs. The phylogenetic analysis using the 16s rRNA genes, the UBCGs and the TYGS database indicated that XH36 belongs to a novel Halomonas species, which we named as Halomonas qaidamensis. Osmoadaptation related genes including Na(+) and K(+) transport and compatible solute accumulation were both present in the XH36 genome, the latter of which mainly contained ectoine, 5-hydroxyectoine and betaine. HPLC validation studies showed that H. qaidamensis XH36 accumulated ectoine to cope with salt stress, and the content of ectoine could be as high as 315 mg/g CDW under 3 mol/l NaCl. Our results show that XH36 is a new promising industrial strain for ectoine production, and the genomic analysis will guide us to better understand its salt-induced osmoadaptation mechanisms, and provide theoretical references for future application research of ectoine.

Indexed as

Amino Acids, DiaminoHalomonasPhylogenyRNA, Ribosomal, 16SWhole Genome SequencingAmino Acids, DiaminoectoineRNA, Ribosomal, 16SEctoineHalomonasSalt-induced osmoadaptationWhole genome sequencing

Identifiers

PMID35243586
OpenAlexW4214924866

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.