Evidence map›Paper›PMID 35243416›Full record

ArticleCell reports. Medicine2022

Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma.

Hareth Nahi, Michael Chrobok, Stephan Meinke, Charlotte Gran, Nicole Marquardt, Gabriel Afram, Tolga Sutlu, Mari Gilljam, Birgitta Stellan, Arnika K Wagner and 13 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 55 citations in OpenAlex.

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  16. Current Novel Targeted Therapeutic Strategies in Multiple Myeloma.International journal of molecular sciences · 2024
    Review
  17. Natural killer cell-related anti-tumour adoptive cell immunotherapy.Journal of cellular and molecular medicine · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Hareth NahiCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Michael ChrobokCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Stephan MeinkeCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Charlotte GranCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Nicole MarquardtCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Gabriel AframCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Tolga SutluCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Mari GilljamCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Birgitta StellanCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Arnika K WagnerCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Pontus BlombergVecura, Department of Laboratory Medicine, Karolinska Institutet, SE-14186 Stockholm, Sweden.
Per-Henrik HolmqvistVecura, Karolinska Cell Therapy Center, Karolinska University Hospital, SE-14186 Stockholm, Sweden.
Lilian Walther-JallowDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Karin MellströmXNK Therapeutics AB, Hälsovägen 7, Novum, SE-14157 Huddinge, Sweden.
Johan LiwingXNK Therapeutics AB, Hälsovägen 7, Novum, SE-14157 Huddinge, Sweden.
Charlotte GustafssonCenter for Hematology and Regenerative Medicine, Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Robert MånssonCenter for Hematology and Regenerative Medicine, Division of Clinical Immunology and Transfusion Medicine, Department of Laboratory Medicine, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Monika KlimkowskaPathology Unit, Department of Laboratory Medicine, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Gösta GahrtonCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Johan LundCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Per LjungmanDepartment of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska University Hospital Huddinge, SE-14186 Huddinge, Sweden.
Hans-Gustaf LjunggrenCenter for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Evren AliciCenter for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institutet, SE-14183 Huddinge, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few approaches have been made toward exploring autologous NK cells in settings of cancer immunotherapy. Here, we demonstrate the feasibility of infusing multiple doses of

Indexed as

Hematopoietic Stem Cell TransplantationMultiple MyelomaConsolidation ChemotherapyGranzymesHumansKiller Cells, NaturalStem Cell TransplantationTransplantation, AutologousGranzymesadoptive cell therapyconsolidationgranzyme BhematologyimmunotherapyimmunotypingmyelomaNK cells

Identifiers

PMID35243416
PMCPMC8861830
OpenAlexW4210738494

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.