Evidence map›Paper›PMID 35243368›Full record

ArticleSTAR protocols2022

A protocol for studying glucose homeostasis and islet function in mice.

Dana Al Rijjal, Michael B Wheeler

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

  1. The novel adipokine Placin regulates glucose homeostasis via insulin secretion and IGF1 receptor signaling.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Therapeutic Potential of Myricitrin in aMolecules (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Heliyon · 2024
    Article
  19. Article
  20. Loss of Lkb1 in CD11cCellular and molecular life sciences : CMLS · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dana Al RijjalDepartment of Physiology, University of Toronto, 1 King's College Circle, Medical Science Building Rm#3352, Toronto, ON M5S 1A8, Canada.
Michael B WheelerDepartment of Physiology, University of Toronto, 1 King's College Circle, Medical Science Building Rm#3352, Toronto, ON M5S 1A8, Canada.
Canada Research Chairs · CAToronto General Hospital · CA

Funding

CIHR FDN-143219
6 · The paper itself

Abstract

Glucose tolerance test and glucose stimulated insulin secretion are important measures to determine glucose homeostasis and islet function and assess diabetes. Here, we provide a protocol where glucose tolerance test is used to study glucose homeostasis and insulin secretion in vivo, followed by islet isolation and glucose stimulated insulin secretion to determine islet function ex vivo. This protocol enables evaluation of glucose homeostasis and islets in mice which can also be applied to rat, beta cell lines and human studies. For complete details on the use and execution of this profile, please refer to Al Rijjal et al. (2021).

Indexed as

Islets of LangerhansAnimalsGlucoseHomeostasisInsulinInsulin SecretionMiceRatsGlucoseInsulinCell BiologyCell isolationMetabolismModel Organisms

Identifiers

PMID35243368
PMCPMC8857654
OpenAlexW4212834747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.