Evidence map›Paper›PMID 35243169›Full record

ArticleAmerican journal of ophthalmology case reports2022

The multifaceted presentation of syphilitic chorioretinitis examined by multimodal imaging: A case series.

Lorenzo Ferro Desideri, Raffaella Rosa, Donatella Musetti, Aldo Vagge, Antonio Vena, Matteo Bassetti, Carlo Enrico Traverso, Massimo Nicolò

Abstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lorenzo Ferro DesideriUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Raffaella RosaUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Donatella MusettiUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Aldo VaggeUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Antonio VenaInfectious Diseases Clinic, Department of Health Sciences, University of Genova and Ospedale Policlinico San Martino - IRCCS per l'Oncologia, Genoa, Italy.
Matteo BassettiInfectious Diseases Clinic, Department of Health Sciences, University of Genova and Ospedale Policlinico San Martino - IRCCS per l'Oncologia, Genoa, Italy.
Carlo Enrico TraversoUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Massimo NicolòUniversity Eye Clinic of Genoa, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular syphilis is also known as the 'great masquerader' for the wide variety of clinical features associated with this infection. Although chorioretinitis represents the most frequent manifestation in the posterior pole, other clinical entities can be described, including retinal vasculitis, optic disc disorders, necrotizing vasculitis and acute syphilitic posterior placoid chorioretinopathy (ASPPC).
This latter is an infrequent ocular manifestation of syphilis, whose pathophysiology remains still unknown; however, multimodal imaging, including optical coherence tomography angiography (OCTA), has enabled us to better describe its pathophysiology and clinical course.
In this study we report a case series of 3 different patients with syphilis-related chorioretinopathies; in this regard, the role of multimodal imaging has emerged has an extremely useful approach in order to better understand the pathophysiology of syphilitic chorioretinopathies. This could help clinicians (both ophthalmologist and infectious disease specialists) to early treat and prevent the severe ocular complications related to this fearsome disease.

Indexed as

ChorioretinitisMultimodal imagingoctOcular syphilisUveitis

Identifiers

PMID35243169
PMCPMC8866844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.