Evidence map›Paper›PMID 35243027›Full record

ArticleClinical and translational radiation oncology2022

Outcomes and toxicities in oligometastatic patients treated with stereotactic body radiotherapy for adrenal gland metastases: A multi-institutional retrospective study.

A Baydoun, H Chen, I Poon, S Badellino, R Dagan, D Erler, M C Foote, A V Louie, K J Redmond, U Ricardi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. ADVANCES IN RADIOTHERAPY OF ADRENAL GLAND LESIONS.Acta endocrinologica (Bucharest, Romania : 2005)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

A BaydounDepartment of Radiation Oncology, University Hospitals of Cleveland, Cleveland, OH 44106, USA.
H ChenDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
I PoonDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
S BadellinoRadiation Oncology Unit, Department of Oncology, University of Turin and Città della Salute e della Scienza Hospital, Via Genova 3, Turin 10126, Italy.
R DaganDepartment of Radiation Oncology, University of Florida Health Proton Therapy Institute, Jacksonville, FL 32206, United States.
D ErlerDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
M C FooteDepartment of Radiation Oncology, Princess Alexandra Hospital, Woolloongabba, QLD 4120, Australia.
A V LouieDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
K J RedmondDepartment of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University, Baltimore, MD 21218, United States.
U RicardiRadiation Oncology Unit, Department of Oncology, University of Turin and Città della Salute e della Scienza Hospital, Via Genova 3, Turin 10126, Italy.
A SahgalDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Ontario M4N 3M5, Canada.
T BiswasDepartment of Radiation Oncology, University Hospitals of Cleveland, Cleveland, OH 44106, USA.
Health Sciences Centre · CASunnybrook Health Science Centre · CAUniversity Hospitals of Cleveland · USUniversity of Turin · ITJohns Hopkins University · USPrincess Alexandra Hospital · AUUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies reporting SBRT outcomes in oligometastatic patients with adrenal gland metastases (AGM) are limited. Herein, we present a multi-institutional analysis of oligometastatic patients treated with SBRT for AGM. MATERIAL/

methodsThe Consortium for Oligometastases Research (CORE) is among the largest retrospective series of patients with oligometastases. Among CORE patients, those treated with SBRT for AGM were included. Clinical and dosimetric data were collected. Adrenal metastatic burden (AMB) was defined as the sum of all adrenal GTV if more than one oligometastases is present.Competing risk analysis was used to estimate actuarial cumulative local recurrence (LR) and widespread progression (WP). Kaplan-Meier method was used to report overall survival (OS), local recurrence-free survival (LRFS), and progression-free survival (PFS). Treatment related toxicities were also reported.

resultsThe analysis included 47 patients with 57 adrenal lesions. Median follow-up was 18.2 months. Median LRFS, PFS, and OS were 15.3, 5.3, and 19.1 months, respectively. A minimum PTV dose BED

conclusionSBRT to AGM achieved a satisfactory local control and OS in oligometastatic patients. High minimum PTV dose and BED

Indexed as

Adrenal gland metastasesOligometastasesSBRT

Identifiers

PMID35243027
PMCPMC8885400
OpenAlexW4200319383

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.