Evidence map›Paper›PMID 35243017›Full record

ArticleClinical and translational radiation oncology2022

GEC ESTRO ACROP consensus recommendations for contact brachytherapy for rectal cancer.

Alexandra J Stewart, Evert J Van Limbergen, Jean-Pierre Gerard, Ane L Appelt, Frank Verhaegen, Maaike Berbee, Te Vuong, Ciarna Brooker, Tim Rockall, Arthur Sun Myint

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Elderly Rectal Cancer: An Updated Review.Current oncology reports · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 4 countries.

Alexandra J StewartSt Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, England, United Kingdom.
Evert J Van LimbergenDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Jean-Pierre GerardCentre Antoine LACASSAGNE, Nice, France.
Ane L AppeltLeeds Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
Frank VerhaegenDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Maaike BerbeeDepartment of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Te VuongDept. of Radiation Oncology, Jewish General Hospital, Montreal, Canada.
Ciarna BrookerSt Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, England, United Kingdom.
Tim RockallSt Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, England, United Kingdom.
Arthur Sun MyintClatterbridge Cancer Centre, Liverpool, England, United Kingdom.
Maastro Clinic · NLRoyal Surrey County Hospital · GBCentre Antoine Lacassagne · FRJewish General Hospital · CAMaastricht University Medical Centre · NLSt James's University Hospital · GBUniversity of Liverpool · GBUniversity of Surrey · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo issue consensus recommendations for contact X-Ray brachytherapy (CXB) for rectal cancer covering pre-treatment evaluation, treatment, dosimetric issues and follow-up. These recommendations cover CXB in the definitive and palliative setting.

methodsMembers of GEC ESTRO with expertise in rectal CXB issued consensus-based recommendations for CXB based on literature review and clinical experience. Levels of evidence according to the Oxford Centre for Evidence based medicine guidance are presented where possible.

resultsThe GEC ESTRO ACROP consensus recommendations support the use of CXB to increase the chances of clinical complete remission and cure for patients who are elderly with high surgical risk, surgically unfit or refusing surgery. For palliative treatment, the use of CXB is recommended for symptomatic relief and disease control. The use of CXB in an organ-preservation setting in surgically fit patients is recommended within the setting of a clinical trial or registry.

conclusionsThe GEC ESTRO ACROP recommendations for CXB are provided. Recommendations towards standardisation of reporting and prescription are given. Practitioners are encouraged to follow these recommendations and to develop further clinical trials to examine this treatment modality and increase the evidence base for its use. The routine collection of outcomes both clinical and patient-reported is also encouraged.

Indexed as

ACROP, Advisory Committee for Radiation Oncology PracticecCR, complete clinical responseConsensus recommendationsContact X-Ray brachytherapyCTV, Clinical target volumeCXB, Contact X-ray brachytherapyEBRT, External beam radiotherapyGEC ESTRO, Groupe Européen de CuriethérapieEuropean Society for Radiotherapy and OncologyGTN, Glyceryl-trinitrateGTV, Gross tumour volumekV, KilovoltageMRI, Magnetic resonance imagingNTCP, Normal tissue complication probabilityPapillon treatmentPTV, Planning target volumeRectal cancerTEMS, Transanal endoscopic microsurgeryTME, Total mesorectal excisionUS, Ultrasound

Identifiers

PMID35243017
PMCPMC8885383
OpenAlexW4200230211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.