Evidence map›Paper›PMID 35242938›Full record

ArticleData in brief2022

Transcriptome datasets of neural progenitors and neurons differentiated from induced pluripotent stem cells of healthy donors and Parkinson's disease patients with mutations in the

Ekaterina Novosadova, Ksenia Anufrieva, Elizaveta Kazantseva, Elena Arsenyeva, Viya Fedoseyeva, Ekaterina Stepanenko, Daniil Poberezhniy, Sergey Illarioshkin, Lyudmila Novosadova, Tatiana Gerasimova and 4 more

Abstract read
In one paragraph

Article in Data in brief, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  6. Transcription ofJournal of developmental biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ekaterina NovosadovaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Ksenia AnufrievaFederal Research and Clinical Center of Physical Chemical Medicine of the Federal Medical and Biological Agency of the Russian Federation, Moscow, Russia.
Elizaveta KazantsevaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Elena ArsenyevaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Viya FedoseyevaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Ekaterina StepanenkoInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Daniil PoberezhniyInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Sergey IllarioshkinResearch Center of Neurology, Moscow, Russia.
Lyudmila NovosadovaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Tatiana GerasimovaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Valentina NenashevaInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Igor GrivennikovInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.
Maria LagarkovaFederal Research and Clinical Center of Physical Chemical Medicine of the Federal Medical and Biological Agency of the Russian Federation, Moscow, Russia.
Vyacheslav TarantulInstitute of Molecular Genetics of National Research Centre "Kurchatov Institute", Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a complex systemic disorder caused by neurodegenerative processes in the brain that are mainly characterized by progressive loss of dopaminergic neurons in the substantia nigra. About 10% of PD cases have been linked to specific gene mutations (Zafar and Yaddanapudi, 2022) including the

Indexed as

Induced pluripotent stem cellsNeural progenitorsNextSeq 500 System (Illumina)PARK2Parkinson's diseaseTerminally differentiated neuronsTranscriptome analysis

Identifiers

PMID35242938
PMCPMC8867054

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.