Evidence map›Paper›PMID 35242876›Full record

ReviewBioMed research international2022

Nicotinic Acid Riboside Regulates Nrf-2/P62-Related Oxidative Stress and Autophagy to Attenuate Doxorubicin-Induced Cardiomyocyte Injury.

Linfeng Zou, Bing Liang, YuanZhen Gao, Ting Ye, MengJiao Li, Yukun Zhang, Qi Lu, Xiaokun Hu, Huanting Li, Yang Yuan and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  7. NADAntioxidants (Basel, Switzerland) · 2023
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Linfeng ZouSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.ORCID https://orcid.org/0000-0002-2607-2075
Bing LiangQingdao Cancer Institute, Qingdao 266071, China.
YuanZhen GaoSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Ting YeSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
MengJiao LiSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Yukun ZhangSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Qi LuSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Xiaokun HuSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Huanting LiSchool of Basic Medicine and the Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China.
Yang YuanQingdao Cancer Institute, Qingdao 266071, China.ORCID https://orcid.org/0000-0002-5552-4958
Dongming XingQingdao Cancer Institute, Qingdao 266071, China.ORCID https://orcid.org/0000-0002-2359-0440
Qingdao University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (Dox) is an effective chemotherapeutic drug for the treatment of various cancers. Due to its potential fatal cardiotoxic side effects, the clinical application is often limited. Dexrazoxane (Dex) is the only drug approved by the Food and Drug Administration (FDA) for the prevention of Dox-induced cardiotoxicity but has side effects. Thus, more protective strategies should be explored. If NAD

Indexed as

Antineoplastic AgentsApoptosis Regulatory ProteinsCardiotonic AgentsCardiotoxicityDexrazoxaneDoxorubicinHumansNiacinamideOxidative StressPyridinium CompoundsAntineoplastic AgentsApoptosis Regulatory ProteinsCardiotonic AgentsDexrazoxaneDoxorubicinNiacinamidenicotinamide-beta-ribosidePyridinium Compounds

Identifiers

PMID35242876
PMCPMC8888081
OpenAlexW4212805326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.