Evidence map›Paper›PMID 35242862›Full record

ArticleAnnals of translational medicine2022

A novel algorithm for diagnosis of invasive pulmonary aspergillosis based on pentraxin 3 gene polymorphisms and its adjusted value among autoimmune diseases patients.

Yuetian Yu, Chunyan Liu, Cheng Zhu, Han Zhong, Zhichun Gu, Chunhui Xu, Chun Pan, Zhijun Xu, Zhixiong Wu, Wenjuan Wu and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Yuetian Yu *Department of Critical Care Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chunyan Liu *Department of Emergency, Minhang District Central Hospital, Shanghai, China.
Cheng Zhu *Department of Disease Prevention and Control, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Han ZhongDepartment of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhichun GuDepartment of Pharmacy, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chunhui XuDepartment of Laboratory Medicine, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin, China.
Chun PanDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China.
Zhijun XuDepartment of Critical Care Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhixiong WuDepartment of Critical Care Medicine, Huadong Hospital, Fudan University, Shanghai, China.
Wenjuan WuDepartment of Laboratory Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Liangjing LuDepartment of Rheumatology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNFudan University · CNInstitute of Hematology & Blood Diseases Hospital · CNMinhang District Central Hospital · CNSecond Affiliated Hospital of Zhejiang University · CNShanghai East Hospital · CNZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvasive pulmonary aspergillosis (IPA) is a rapidly progressive and fatal disease for those with autoimmune diseases. The performance of existing diagnostic tools is unsatisfactory, and a novel algorithm based on pentraxin 3 (PTX3) gene polymorphisms with adjusted

methodsLevels of PTX3 and GM were measured in the bronchoalveolar lavage fluid (BALF) and blood samples of patients who had autoimmune diseases with IPA between June 2017 and June 2021. Urea dilution was applied internally to correct the real BALF PTX3 and GM values. Three single-nucleotide polymorphisms (SNPs; rs1840680, rs2305619, and rs3816527) in the PTX3 gene were detected by polymerase chain reaction direct sequencing, and their associations with IPA were evaluated. Receiver operating characteristic (ROC) curves based on different variables were generated to determine the best algorithm for IPA diagnosis.

resultsThis study enrolled 50 patients with IPA and 100 without IPA in the control groups (comprising 50 patients with

conclusionsIt was revealed that our new algorithm based on

Indexed as

autoimmune diseasesgalactomannan (GM)gene polymorphismsInvasive pulmonary aspergillosis (IPA)pentraxin 3 (PTX3)

Identifiers

PMID35242862
PMCPMC8825557
OpenAlexW4205756109

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.