ArticleAnnals of translational medicine2022
Abdominal multiorgan procurement from slaughterhouse pigs: a bespoke model in organ donation after circulatory death for
Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- A standardised and reproducible method forAnnals of translational medicine · 2026Article
- Comparison of "Continuous" and "End-ischemic" Approaches of Oxygenated Hypothermic Machine Perfusion for Pancreas Preservation.Transplantation direct · 2026Article
- Iodinated gadolinium-gold nanomaterial as a multimodal contrast agent for cartilage tissue imaging.APL bioengineering · 2024Article
- Are slaughterhouse-obtained livers suitable for use inThe Journal of international medical research · 2023Article
- Ex Vivo Perfusion of Porcine Pancreas and Liver Sourced from Commercial Abattoirs after Circulatory Death as a Research Resource: A Methodological Study.Methods and protocols · 2023Article
- Article
- CC-4066 therapy delivered to kidneys during cold storage and assessed with normothermic reperfusion is feasible and safe.Frontiers in transplantation · 2023Article
- Ureterorenoscopy during normothermic machine perfusion: effect of varying renal pelvis pressure.BJU international · 2023Article
- From waste to wealth: Repurposing slaughterhouse waste for xenotransplantation.Frontiers in bioengineering and biotechnology · 2023Article
- Kidney Normothermic Machine Perfusion Can Be Used as a Preservation Technique and a Model of Reperfusion to Deliver Novel Therapies and Assess Inflammation and Immune Activation.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdvances in organ preservation, reconditioning and assessment have been driven by the increasing necessity to utilise organs from extended criteria donors, particularly donors after circulatory death. Research efforts in this area have aided translation of machine perfusion technology into clinical practice. Pigs are anatomically and physiologically similar to humans and are an excellent model. However, conducting large animal experimental research is challenging and typically limited by ethical and economic constraints. Here we describe a reproducible, cost-effective multi-organ abdominal procurement model of porcine organs from the slaughterhouse.
methodsDomestic pigs are electrically stunned and exsanguinated following the standard abattoir process. Via a longitudinal midline incision, the thoracoabdominal viscera are removed
resultsThe warm ischaemic time is kept between 15-30 minutes. Using this highly protocolized procurement technique we have procured 12 livers, 162 kidneys and 12 pancreata for research, the majority of which have been utilized for
conclusionsWe have described a reliable and reproducible procedure for abdominal multi-organ procurement from slaughterhouse pigs.
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