Evidence map›Paper›PMID 35242827›Full record

ArticleFrontiers in cardiovascular medicine2022

Biniyam G Demissei, WenJian Lv, Nicholas S Wilcox, Karyn Sheline, Amanda M Smith, Kathleen M Sturgeon, Chris McDermott-Roe, Kiran Musunuru, Bénédicte Lefebvre, Susan M Domchek and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Biniyam G DemisseiDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
WenJian LvDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Nicholas S WilcoxDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Karyn ShelineDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Amanda M SmithDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Kathleen M SturgeonDepartment of Public Health Sciences, Pennsylvania State College of Medicine, Hershey, PA, United States.
Chris McDermott-RoeDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Kiran MusunuruDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Bénédicte LefebvreDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Susan M DomchekAbramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Payal ShahAbramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
Bonnie KyDivision of Cardiology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.
University of Pennsylvania · USHershey (United States) · US

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Diagnosis, Prevention, And Treatment Of Cardiovascular Diseases With Genome EditingR35HL145203 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MUSUNURU, KIRAN · 2019 to 2025
$5.7M
Multimarker Risk Prediction in Cancer Therapy CardiotoxicityR01HL118018 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KY, BONNIE · 2014 to 2018
$3.7M
NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR001878NCATS NIH HHS UL1 TR002014NHLBI NIH HHS R01 HL118018NHLBI NIH HHS R35 HL145203
6 · The paper itself

Abstract

objectiveAnimal models suggest that

methodsIn a single-center cross-sectional study, stage I-III breast cancer survivors were enrolled according to three groups: (1)

resultsSixty-seven women with mean (standard deviation) age of 50 (11) years were included. Age-adjusted left ventricular ejection fraction (LVEF) was lower in participants receiving doxorubicin regardless of

conclusions

Indexed as

anthracyclineBRCA1/2breast cancercardiomyocyteheart failureHER2 therapy

Identifiers

PMID35242827
PMCPMC8885808
OpenAlexW4212989256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.