Evidence map›Paper›PMID 35242726›Full record

ArticleFrontiers in pediatrics2021

A Prospective Cohort Study of the Clinical Predictors of Bacteremia in Under-Five Children With Acute Undifferentiated Fever Attending a Secondary Health Facility in Northwestern Nigeria.

Taofik Oluwaseun Ogunkunle, Timothy Olanrewaju Adedoyin, Samuel Kolade Ernest, Fatimah Hassan-Hanga, Abdulazeez Imam, Rasaq Olaosebikan, Stephen K Obaro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Taofik Oluwaseun OgunkunleDepartment of Paediatrics, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Timothy Olanrewaju AdedoyinDepartment of Paediatrics and Child Health, University of Ilorin/University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Samuel Kolade ErnestDepartment of Paediatrics and Child Health, University of Ilorin/University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Fatimah Hassan-HangaDepartment of Paediatrics and Child Health, Aminu Kano University Teaching Hospital, Kano, Nigeria.
Abdulazeez ImamOxford Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Rasaq OlaosebikanDepartment of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, United States.
Stephen K ObaroDivision of Pediatric Infectious Diseases, Department of Pediatrics/Department of Microbiology and Pathology, University of Nebraska Medical Center, Omaha, NE, United States.
University of Ilorin Teaching Hospital · NGAminu Kano Teaching Hospital · NGThomas Jefferson University · USUniversity of Nebraska Medical Center · USUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildren with acute febrile illness with no localizing signs often receive antibiotics empirically in most resource-poor settings. However, little is known about the burden of bacteremia in this category of patients, and an appraisal is thus warranted. This will guide clinical practice and promote rational antibiotics use.

methodsWe prospectively followed up 140 under-five children who presented with acute undifferentiated fever at the emergency/outpatient pediatric unit of a secondary healthcare facility. Baseline clinical and laboratory information was obtained and documented in a structured questionnaire. We compared baseline characteristics between participants with bacteremia and those without bacteremia. We further fitted a multivariable logistic regression model to identify factors predictive of bacteremia among the cohort.

resultThe prevalence of bacteremia was 17.1%, and

conclusionAmong under-five children with acute undifferentiated fever, longer duration of fever, lethargy, inpatient care, tachypnea, and lymphopenia were the significant predictors of bacteremia.

Indexed as

acute undifferentiated feverbacteraemialethargylymphopeniaSalmonellaunder-five children

Identifiers

PMID35242726
PMCPMC8885983
OpenAlexW4213068303

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.