ArticleGland surgery2022
Pathological and imaging features of Paget's disease and nipple adenoma: a comparative study.
Article in Gland surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Nipple adenoma mimicking Paget's disease: a case report.Korean journal of clinical oncology · 2026Article
- Diagnostic imaging challenges of mammary Paget's disease presenting with subtle clinical and imaging features: A case report.Radiology case reports · 2025Article
- An update on multimodal imaging strategies for nipple discharge: from detection to decision.Insights into imaging · 2025Article
- Review
- Nipple adenoma detected by multimodal ultrasound: a case report and literature review.Frontiers in oncology · 2024Article
- The effects of clinicopathological and imaging findings on recurrence and survival in mammary Paget's disease.Northern clinics of Istanbul · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth Paget's disease (PD) and nipple adenoma (NA) are rare lesions occurred on nipple and share some similarities in clinical manifestations, but there are have different pathological manifestations and imaging findings. This study analyzed the clinicopathological and imaging features of PD in nipple and NA to improve our knowledge about these two diseases and to provide guidance for clinical diagnosis and treatment.
methodsRetrospectively analyzed 99 female patients confirmed by surgery and pathology from January 2014 to December 2018. The features of imaging examination included 95 cases of breast ultrasound, 83 cases of breast X-ray and 24 cases of magnetic resonance imaging (MRI) were analyzed and compered the detection rate and diagnostic accuracy.
resultsThe 99 patients consisted of 76 patients with PD and 23 patients with NA. Despite the similarity of clinical manifestations between PD and NA, the pathological features of these diseases were completely different. Differences in various imaging manifestations were found to facilitate differential diagnosis. Breast X-ray and ultrasound can discover the nipple areola changes such as mass and calcification, but some cases still show negative. Breast MRI can clearly show the areola lesions of nipple PD and NA, accurately evaluate the degree and size of breast lesions, and help clinicians choose appropriate and personalized diagnosis and treatment methods.
conclusionsThe combination of multiple breast imaging examinations (including X-ray, ultrasound, and MRI) can improve the diagnosis of PD and NA and play a guiding role in the options for clinical treatment.
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