Evidence map›Paper›PMID 35242677›Full record

ArticleGland surgery2022

The expression of m

Yutong Yao, Le Luo, Guangming Xiang, Junjie Xiong, Nengwen Ke, Chunlu Tan, Yonghua Chen, Xubao Liu

Open access · diamondAbstract read
In one paragraph

Article in Gland surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Role of the mInternational journal of molecular medicine · 2025
    Review
  7. Article
  8. NTranslational cancer research · 2023
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yutong Yao *Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Le Luo *Department of Hepatobiliary and Pancreatic Surgery Center, Cell Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Guangming Xiang *Department of Hepatobiliary and Pancreatic Surgery Center, Cell Transplantation Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Junjie XiongDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Nengwen KeDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Chunlu TanDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Yonghua ChenDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xubao LiuDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNUniversity of Electronic Science and Technology of China · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between N6-methyladenosine (m

methodsHere, we systematically evaluated the expression of 19 m

resultsWe found two subgroups with dramatically different immune landscapes and prognoses. Subsequently, differences in independent prognostic parameters, risk score distribution, survival, and cluster analysis between the high-risk and low-risk groups were found. Moreover, these gene signatures displayed good discriminative performances in the GEO datasets. We also found that the risk score was positively correlated with the tumor mutation burden (TMB), and the TMB value was higher in the high-risk scoring group. The low-risk scoring group was linked by a stronger response to anti-programmed cell death ligand 1 (anti-PD-L1) immunotherapy and clinical advantages in the immunotherapeutic advanced urothelial cancer (IMvigor210) cohort. Ultimately, we found that these 5 m

conclusionsThe construction signature based on the m

Indexed as

consensus clusteringm6A methylation regulatorsoverall survivalPancreatic ductal adenocarcinoma (PDAC)tumor immune microenvironment

Identifiers

PMID35242677
PMCPMC8825516
OpenAlexW4205120892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.