Evidence map›Paper›PMID 35242602›Full record

ArticleSchizophrenia research. Cognition2022

Verbal memory performance predicts remission and functional outcome in people at clinical high-risk for psychosis.

Emily P Hedges, Hannah Dickson, Stefania Tognin, Gemma Modinos, Mathilde Antoniades, Mark van der Gaag, Lieuwe de Haan, Patrick McGorry, Christos Pantelis, Anita Riecher-Rössler and 12 more

Open access · goldAbstract read
In one paragraph

Article in Schizophrenia research. Cognition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  7. Article
  8. Article
  9. Assessing Cannabis Use in People with Psychosis.Cannabis and cannabinoid research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 11 countries.

Emily P HedgesDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Hannah DicksonDepartment of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Stefania TogninDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Gemma ModinosDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Mathilde AntoniadesDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY 10029, United States.
Mark van der GaagVU University, Faculty of Behavioural and Movement Sciences, Department of Clinical Psychology and EMGO+ Institute for Health and Care Research, van der Boechorststraat 1, 1081, BT, Amsterdam, the Netherlands.
Lieuwe de HaanAmsterdam UMC, Department Early Psychosis, Meibergdreef 5, 1105, AZ, Amsterdam, the Netherlands.
Patrick McGorryCentre for Youth Mental Health, University of Melbourne, 35 Poplar Road (Locked Bag 10), Parkville, Victoria 485 3052, Australia.
Christos PantelisMelbourne Neuropsychiatry Centre, University of Melbourne & Melbourne Health, Carlton South, Vic, Australia.
Anita Riecher-RösslerUniversity of Basel, Faculty of Medicine, Basel, Switzerland.
Rodrigo BressanLiNC - Lab Interdisciplinar Neurociências Clínicas, Depto Psiquiatria, Escola Paulista de Medicina, Universidade Federal de São Paulo - UNIFESP, Brazil.
Neus Barrantes-VidalDepartament de Psicologia Clínica i de la Salut (Universitat Autònoma de Barcelona), Fundació Sanitària Sant Pere Claver (Spain), Spanish Mental Health Research Network (CIBERSAM), Spain.
Marie-Odile KrebsUniversity of Paris, GHU Psychiatrie et Neurosciences of Paris, Sainte-Anne, C'JAAD, pôle PEPIT, Inserm 1266, Institut de Psychiatrie (CNRS 3557), Paris, France.
Merete NordentoftMental Health Center Copenhagen and Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research, CINS, Mental Health Center Glostrup, Mental Health Services in the Capital Region of Copenhagen, University of Copenhagen, Denmark.
Stephan RuhrmannDepartment of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital, University of Cologne, Cologne, Germany.
Gabriele SachsMedical University of Vienna, Department of Psychiatry and Psychotherapy, Austria.
Bart P RuttenDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, P.O. Box 616, 6200 MD 464 Maastricht, the Netherlands.
Jim van OsDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
EU-GEI High Risk Study
Lucia R ValmaggiaDepartment of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Philip McGuireDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
Matthew J KemptonDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, United Kingdom.
King's College London · GBArkin · NLCentro de Investigación Biomédica en Red de Salud Mental · ESIcahn School of Medicine at Mount Sinai · USMaastricht University Medical Centre · NLMedical University of Vienna · ATMelbourne Health · AUParnassia Groep · NLUniversidade Federal de São Paulo · BRUniversité Paris Cité · FRUniversity Hospital Cologne · DEUniversity of Amsterdam · NLUniversity of Basel · CHUniversity of Copenhagen · DKUniversity of Melbourne · AU

Funding

Medical Research Council MR/J008915/1Medical Research Council MR/N026063/1
6 · The paper itself

Abstract

Robust deficits in cognitive functioning are present in people with psychosis and are evident in the early stages of the disorder. Impairments in verbal memory and verbal fluency are reliably seen in individuals at clinical high-risk for psychosis (CHR) compared to healthy populations. As previous studies have shown a relationship between cognition and longer-term outcomes in schizophrenia, the aim of this paper was to explore whether verbal memory and verbal fluency performance predicted outcomes in a large CHR sample recruited as part of the EU-GEI High Risk Study. Participants included 316 CHR individuals, 90.8% of whom were not currently on antipsychotic medication, and 60 healthy controls. Verbal memory and verbal fluency performance were measured at baseline. At two-year follow-up, CHR individuals were assessed by three different outcome measures, those who did and did not (1) transition to psychosis, (2) experience burdening impairment or disabilities, or (3) remit clinically from CHR status. Individuals with CHR displayed significant verbal memory and verbal fluency deficits at baseline compared to healthy controls (Hedges'

Indexed as

CognitionEarly interventionProdromeTransitionVerbal fluency

Identifiers

PMID35242602
PMCPMC8861401
OpenAlexW3210464709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.