Evidence map›Paper›PMID 35242500›Full record

ArticlePreventive medicine reports2022

Protocol: A randomized controlled trial to assess effectiveness of a 12-month lifestyle intervention to reduce cardiovascular disease risk in families ten years after pre-eclampsia (FINNCARE).

Tiina Jääskeläinen, Anni Kivelä, Michelle Renlund, Seppo Heinonen, Minna Aittasalo, Hannele Laivuori, Taisto Sarkola

Open access · goldAbstract read
In one paragraph

Article in Preventive medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Preeclampsia-exposed children's heart rate variability 8-12 yr after index pregnancy: FINNCARE study.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tiina JääskeläinenMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Anni KiveläMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Michelle RenlundChildren's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Seppo HeinonenDepartment of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland.
Minna AittasaloUKK Institute for Health Promotion Research, Tampere, Finland.
Hannele LaivuoriMedical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Taisto SarkolaChildren's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIUrho Kaleva Kekkonen Institute · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pre-eclampsia (PE) is a multisystem progressive disorder affecting 3-5% of pregnancies. PE independently increases the risk for premature cardiovascular disease (CVD) in mothers and their children long-term. The effectiveness of a family-centered lifestyle intervention to lower CVD risk in PE families has not previously been evaluated. In the current FINNCARE study, we prospectively compare CVD risk and CVD progression in PE families (mother, father and child) in a cross-sectional study setting 8-12 years from delivery with non-PE control families of comparable age. Furthermore, we evaluate the effectiveness and feasibility of an interactive web-based behavioral 12-month lifestyle intervention to reduce blood pressure and the CVD risk profile overall in a randomized controlled trial. In total, 300 PE families will be randomized 1:1 to a PE-intervention or a PE-control group, and the 100 non-PE control families similarly followed-up at 12 months. Primary outcome is 24-hour mean systolic BP change from baseline in mother and child. Study aims to provide information on CVD progression and CVD risk management in the family following PE.

Indexed as

BCW, Behaviour Change WheelBMI, body mass indexBP, blood pressureCardiovascular diseaseCVD, cardiovascular diseaseDASH, Dietary Approaches to Stop HypertensionFamilyFFQ, food frequency questionnaireFINNPEC, The Finnish Genetics of Pre-eclampsia ConsortiumHRV, heart rate variabilityIPAQ, International Physical Activity QuestionnaireLifestyle interventionPE, pre-eclampsiaPre-eclampsiaPrevention

Identifiers

PMID35242500
PMCPMC8861388
OpenAlexW4210908415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.