Evidence map›Paper›PMID 35242409›Full record

ArticleSurgical neurology international2022

From a dysembryoplastic neuroepithelial tumor to a glioblastoma multiforme: Pitfalls of initial diagnosis on biopsy material, a case report.

Rutger J Slegers, Jan Beckervordersandforth, Ann Hoeben, Govert Hoogland, Martijn P G Broen, Monique Anten, Jim T A Dings, Piet van den Ende, Wouter J P Henneman, Olaf E M G Schijns

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In one paragraph

Article in Surgical neurology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rutger J SlegersDepartment of Neurosurgery, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Jan BeckervordersandforthDepartment of Pathology, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Ann HoebenDepartment of Medical Oncology Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Govert HooglandDepartment of Neurosurgery, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Martijn P G BroenDepartment of Neurology, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Monique AntenDepartment of Neurology, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Jim T A DingsDepartment of Neurosurgery, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Piet van den EndeDepartment of Radiotherapy, Maastro Clinic, Maastricht, Limburg, Netherlands.
Wouter J P HennemanDepartment of Radiology and Nuclear, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Olaf E M G SchijnsDepartment of Neurosurgery, Medicine Maastricht University Medical Center, Maastricht, Limburg, Netherlands.
Maastricht University Medical Centre · NLMaastro Clinic · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGanglioglioma (GG) and dysembryoplastic neuroepithelial tumor (DNET) belong to the group of low-grade epilepsy-associated tumors (LEAT) and are the most prevalent tumor types found in patients undergoing epilepsy surgery. Histopathological differentiation between GG and DNET can be difficult on biopsies due to limited tumor tissue. CASE DESCRIPTION: Here, we present a rare case where a low-grade tumor was initially classified as DNET, based on biopsy findings and unfortunately dedifferentiated within 10 years into a glioblastoma multiforme. After gross total resection, the initial tumor was reclassified as GG.

conclusionThis case illustrates the diagnostic challenges of LEAT, especially on biopsy material. Therefore, we advocate to counsel for complete resection and histopathological diagnosis utilizing tumor markers to confirm the nature of the tumor and to advice type of follow-up and eventual concurrent treatment.

Indexed as

Dysembryoplastic neuroepithelial tumorGangliogliomaGlioblastomaLow-grade epilepsy-associated tumorTemporal lobe epilepsy

Identifiers

PMID35242409
PMCPMC8888280
OpenAlexW4211017064

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.