ArticleJournal of thoracic disease2022
Differentiation between staple line granuloma and recurrence after sublobar resection for primary lung cancer.
Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Article
- Staple-line-associated lung adenocarcinoma years after video-assisted thoracoscopic surgical bullectomy for pneumothorax.Respiratory medicine case reports · 2026Article
- Completion lobectomy following segmentectomy for malignant lung tumors: a multi-institutional study of surgical feasibility, oncologic outcomes, and diagnostic challenges (ESSG-02 study).Translational lung cancer research · 2025Article
- Completion lobectomy after thoracoscopic segmentectomy on the left side should be approached with thoracotomy.Journal of thoracic disease · 2025Article
- Diagnostic utility of bronchoscopy for newly emerging peripheral pulmonary lesions after pulmonary resection.Translational lung cancer research · 2025Article
- Medical management of post-sublobar resection pulmonary granulomatous lesion: a report of two cases.Surgical case reports · 2024Article
- Delayed severe hemothorax caused by a staple line of a bullectomy performed 11 years earlier.Surgical case reports · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of sublobar resection for early-stage lung cancer or frail cases that cannot tolerate radical surgery for primary lung cancer has been increasing. This study aimed to identify the frequency, shape, and course of staple line thickening and granuloma formation after sublobar resection for primary lung cancer, and to identify factors that help distinguish them from recurrent cancer cases.
methodsThe medical records of 64 patients who underwent sublobar resection for primary lung cancer from January 2012 to December 2017 at our institution were retrospectively reviewed. Computed tomography (CT) images taken every 6 months for at least 3 years after surgery were reviewed, and the postoperative course was examined.
resultsStaple line thickening at the time of the first CT scan after surgery was observed in 43 cases (67.2%). Of them, linear thickening was seen in 31 cases (72.1%), and nodular thickening was seen in 12 cases (27.9%). Of these 43 cases, 25 cases were decreased, 8 cases were unchanged and 10 cases showed a tendency to progress during the follow-up period. Of the 64 cases, 7 (10.9%) had staple line recurrence. Staple line recurrence was significantly correlated with vascular invasion (P=0.015), surgical margin (P=0.013), nodular thickening (P<0.001) and a tendency to show progressive thickening (P<0.001).
conclusionsStaple line thickening was observed in many cases of sublobar resection, and most of them were linear thickening. Staple line recurrence should be suspected if nodular thickening appears and shows a tendency to progress.
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