Evidence map›Paper›PMID 35242364›Full record

ArticleJournal of thoracic disease2022

Intercostal nerve blockade with liposomal bupivacaine reduces length of stay after video assisted thoracic surgery (VATS) lobectomy.

Kian Banks, Sora Ely, Diana S Hsu, Dana A Dominguez, Rebecca C Gologorsky, Julia Wei, Clara Maxim, Simon K Ashiku, Ashish R Patel, Jeffrey B Velotta

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kian BanksDepartment of Surgery, UCSF East Bay, Oakland, CA, USA.
Sora ElyDepartment of Surgery, UCSF East Bay, Oakland, CA, USA.
Diana S HsuDepartment of Surgery, UCSF East Bay, Oakland, CA, USA.
Dana A DominguezDepartment of Surgery, UCSF East Bay, Oakland, CA, USA.
Rebecca C GologorskyDepartment of Surgery, UCSF East Bay, Oakland, CA, USA.
Julia WeiDivision of Research, Biostatistical Consulting Unit, Kaiser Permanente Northern California, Oakland, CA, USA.
Clara MaximDivision of Research, Biostatistical Consulting Unit, Kaiser Permanente Northern California, Oakland, CA, USA.
Simon K AshikuDepartment of Thoracic Surgery, Kaiser Permanente Northern California, Oakland, CA, USA.
Ashish R PatelDepartment of Thoracic Surgery, Kaiser Permanente Northern California, Oakland, CA, USA.
Jeffrey B VelottaDepartment of Thoracic Surgery, Kaiser Permanente Northern California, Oakland, CA, USA.
Kaiser Permanente · USCalifornia State University, East Bay · USBiostatistical Consulting (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntercostal nerve blockade (INB) for thoracic surgery analgesia has gained popularity in practice, but evidence demonstrating its efficacy remains sparse and inconsistent. We investigated the effect of INB with standard bupivacaine (SB) with epinephrine versus liposomal bupivacaine (LB) versus a mixed solution of the two on postoperative pain control and outcomes in video assisted thoracoscopic lobectomy patients.

methodsSince 2014, our practice has shifted from using INBs with SB with epinephrine, to LB, to a mix of the two as the central component of multimodal analgesia after video assisted thoracoscopic surgery. The blocks are performed in a standardized fashion under thoracoscopic visualization consecutively from two rib spaces above to two below the outermost incisions. We retrospectively compared all minimally invasive lobectomies performed at our institution between January 2014 and July 2018 by type of local anesthetic used for INB. We examined median length of stay (LOS), opioid utilization, and subjective pain scores [0-10].

resultsOut of 302 minimally invasive lobectomy patients, 34 received SB with epinephrine, 222 received LB alone, and 46 received the mixed solution. LOS was almost a full day shorter in the LB group than in the SB group (34.8

conclusionsOur study is by far the largest (N=302) to compare types of local anesthetic used for INB within a uniform case population. The reductions in LOS and opiate utilization observed in our study among patients receiving LB-based formulations were both statistically and clinically significant.

Indexed as

analgesiaLungpainthoracoscopyvideo assisted thoracic surgery (VATS)

Identifiers

PMID35242364
PMCPMC8828528
OpenAlexW4206808744

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.