Evidence map›Paper›PMID 35242296›Full record

ArticleJournal of healthcare engineering2022

Correlation of HMGB1, PON-1, MCP-1, and Periodontal

Zhen-Ai Jin, Ying Li, Wei-Bing Chen, Yu-Ying Wang, Yi-Kun Zhao, Xiang-Lan Sun, Jia-Jun He, Guo Jie, Yu-Mei Sun

Open access · hybridAbstract read
In one paragraph

Article in Journal of healthcare engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zhen-Ai JinDepartment of Pediatrics, Affiliated Hospital of Yanbian University, 1327 Bureau Street, Jilin, Yanji, China.ORCID 0000-0002-9469-9769
Ying LiDepartment of Pediatrics, Affiliated Hospital of Yanbian University, 1327 Bureau Street, Jilin, Yanji, China.
Wei-Bing ChenNeonatology Department, Rizhao People's Hospital of Jining Medical University, No. 126,Taian Road, Rizhao, Shandong, China.
Yu-Ying WangJilin Provincial People's Hospital, 1183 Gongnong Street, Chaoyang, Changchun, China.
Yi-Kun ZhaoNeonatology Department, Rizhao People's Hospital of Jining Medical University, No. 126,Taian Road, Rizhao, Shandong, China.
Xiang-Lan SunObstetrical Department, Rizhao People's Hospital of Jining Medical University, No. 126,Taian Road, Rizhao, Shandong, China.
Jia-Jun HeObstetrical Department, Rizhao People's Hospital of Jining Medical University, No. 126,Taian Road, Rizhao, Shandong, China.
Guo JieDepartment of Obstetrics, Affiliated Hospital of Yanbian University, 1327 Bureau Street, Yanji, Jilin, China.
Yu-Mei SunDepartment of Neonatology, Dalian Women and Children's Medical Center (Group), No. 1 Dunhuang Road, Dalian Liaoning, China.
People’s Hospital of Rizhao · CNYanbian University Hospital · CNDalian Medical University · CNPeople 's Hospital of Jilin Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis paper aims to investigate the correlation between high mobility group protein-1 (HMG-b1), antioxidant enzyme-1 (paraoxon-1, PON-1), monocyte chemoattractant protein-1 (monocyte chemoattractant protein-1, MCP-1), MATERIALS AND

methodsThe total sample size comprised of 73 cases in both groups. These patients were further subdivided into 2 groups: the MSAF group and the control group. 38 women were in the MSAF group and 35 women with term amniotic fluid serum were in the control group. The MSAF group was selected as a full-term singleton amniotic fluid fecal infection group. Clinical data were collected, and specimens were collected. Fecal staining of amniotic fluid and full-term amniotic fluid removes the placenta and umbilical cord blood. The expression of HMGB1 in the placenta was observed by immune-histochemical staining of MSAF and control groups. The content of PON-1 in cord blood was determined by ELISA.

resultsCorrelation between maternal and neonatal clinical data and MSAF was done; MSAF group mean gestational age was 41.38 ± 1.40 weeks; control group mean gestational age was 39.20 ± 1.24 weeks. This study found no correlation between the birth weight, maternal age, sex, first/transmaternal, hyperthyroidism, hypothyroidism, and anemia between the MSAF and control group with nonsignificant

conclusionsGestational age and placental abnormalities are clinical high-risk factors for MSAF. HMGB1, PON-1, MCP-1, and Periodontal

Indexed as

Amniotic FluidAryldialkylphosphataseChemokine CCL2HMGB1 ProteinPorphyromonas gingivalisAntioxidantsBacteroidaceae InfectionsEndothelial CellsFemaleHumansInfantInfant, NewbornMaleMeconiumPeriodontiumPlacentaAntioxidantsAryldialkylphosphataseChemokine CCL2HMGB1 ProteinPON1 protein, human

Identifiers

PMID35242296
PMCPMC8888080
OpenAlexW4212901743

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.