Evidence map›Paper›PMID 35242287›Full record

ArticleComputational and structural biotechnology journal2022

Microtubule assembly and disassembly dynamics model: Exploring dynamic instability and identifying features of Microtubules' Growth, Catastrophe, Shortening, and Rescue.

Evgenii Kliuchnikov, Eugene Klyshko, Maria S Kelly, Artem Zhmurov, Ruxandra I Dima, Kenneth A Marx, Valeri Barsegov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Evgenii KliuchnikovDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854, USA.
Eugene KlyshkoDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854, USA.
Maria S KellyDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.
Artem ZhmurovKTH Royal Institute of Technology, Stockholm, Sweden.
Ruxandra I DimaDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.
Kenneth A MarxDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854, USA.
Valeri BarsegovDepartment of Chemistry, University of Massachusetts, Lowell, MA 01854, USA.
University of Massachusetts Lowell · USUniversity of Cincinnati · USKTH Royal Institute of Technology · SE

Funding

Mechanisms of mechano-chemical rupture of blood clots and thrombiR01HL148227 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PUROHIT, PRASHANT KISHORE · 2020 to 2023
$2.5M
NHLBI NIH HHS R01 HL148227
6 · The paper itself

Abstract

Microtubules (MTs), a cellular structure element, exhibit dynamic instability and can switch stochastically from growth to shortening; but the factors that trigger these processes at the molecular level are not understood. We developed a 3D Microtubule Assembly and Disassembly DYnamics (MADDY) model, based upon a bead-

Identifiers

PMID35242287
PMCPMC8861655
OpenAlexW4210672133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.