Evidence map›Paper›PMID 35242244›Full record

ArticleDisease markers2022

Combination of Prehospital NT-proBNP with qSOFA and NEWS to Predict Sepsis and Sepsis-Related Mortality.

Francisco Martín-Rodríguez, Laura Melero-Guijarro, Guillermo J Ortega, Ancor Sanz-García, Teresa de la Torre de Dios, Jesús Álvarez Manzanares, José L Martín-Conty, Miguel A Castro Villamor, Juan F Delgado Benito, Raúl López-Izquierdo

Open access · hybridAbstract readNews
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Observational
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Francisco Martín-RodríguezUnidad Móvil de Emergencias, Gerencia de Emergencias Sanitarias, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.ORCID https://orcid.org/0000-0002-1773-2860
Laura Melero-GuijarroServicio de Urgencias, Complejo Asistencial Universitario de Palencia, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.
Guillermo J OrtegaUnidad de Análisis de Datos (UAD) del Instituto de Investigación Sanitaria del Hospital de la Princesa (IIS-IP), Madrid, Spain.
Ancor Sanz-GarcíaUnidad de Análisis de Datos (UAD) del Instituto de Investigación Sanitaria del Hospital de la Princesa (IIS-IP), Madrid, Spain.ORCID https://orcid.org/0000-0002-5024-5108
Teresa de la Torre de DiosGerencia de Atención Primaria de Salamanca, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.
Jesús Álvarez ManzanaresServicio de Urgencias, Hospital Universitario Rio Hortega de Valladolid, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.ORCID https://orcid.org/0000-0003-3914-2383
José L Martín-ContyFaculty of Health Sciences, Universidad de Castilla la Mancha, Talavera de la Reina, Spain.ORCID https://orcid.org/0000-0001-8579-2323
Miguel A Castro VillamorCentro de Simulación Clínica Avanzada, Departamento de Medicina, Dermatología y Toxicología, Universidad de Valladolid, Spain.ORCID https://orcid.org/0000-0001-9910-427X
Juan F Delgado BenitoUnidad Móvil de Emergencias, Gerencia de Emergencias Sanitarias, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.ORCID https://orcid.org/0000-0002-0811-1448
Raúl López-IzquierdoServicio de Urgencias, Hospital Universitario Rio Hortega de Valladolid, Gerencia Regional de Salud de Castilla y León (SACYL), Spain.ORCID https://orcid.org/0000-0001-5092-4138
Hospital Universitario de La Princesa · ESHospital Universitario Río Hortega · ESJunta de Castilla y León · ESUniversidad de Valladolid · ESComplejo Asistencial Universitario de Palencia · ESUniversity of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the role of prehospital point-of-care

methodsA prospective, emergency medical service-delivered, prognostic, cohort study of adults evacuated by ambulance and admitted to emergency department between January 2020 and May 2021. The discriminative power of the predictive variable was assessed through a prediction model trained using the derivation cohort and evaluated by the area under the curve of the receiver operating characteristic on the validation cohort.

resultsA total of 1,360 patients were enrolled with medical disease in the study. The occurrence of sepsis, septic shock, and in-hospital sepsis-related mortality was 6.4% (67 cases), 4.2% (44 cases), and 6.1% (64 cases). Prehospital National Early Warning Score 2 had superior predictive validity than quick Sequential Organ Failure Assessment and

conclusionsThe incorporation of

Indexed as

Hospital MortalityNatriuretic Peptide, BrainOrgan Dysfunction ScoresPeptide FragmentsPredictive Value of TestsAgedEmergency Medical ServicesEmergency Service, HospitalFemaleHospitalizationHumansMalePrognosisProspective StudiesSepsisNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)

Identifiers

PMID35242244
PMCPMC8886755
OpenAlexW4213423402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.