Evidence map›Paper›PMID 35242233›Full record

ArticleOncology letters2022

Evaluation of the expression of fatty acid synthase and

Sadia Raab, Ninon Very, Belinda Duchêne, Pierre Rybarczyk, Nicolas Jonckheere, Ikram El Yazidi-Belkoura, Tony Lefebvre

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Mammalian fatty acid synthase andBiochemistry and biophysics reports · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Sadia RaabUniversité de Lille, CNRS, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, F-59000 Lille, France.
Ninon VeryUniversité de Lille, CNRS, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, F-59000 Lille, France.
Belinda DuchêneUniversité de Lille, CNRS, Inserm, CHU Lille, UMR 9020-U1277, CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.
Pierre RybarczykService d'Anatomie et Cytologie Pathologique, CHU Amiens-Picardie, F-80000 Amiens, France.
Nicolas JonckheereUniversité de Lille, CNRS, Inserm, CHU Lille, UMR 9020-U1277, CANTHER-Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.
Ikram El Yazidi-BelkouraUniversité de Lille, CNRS, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, F-59000 Lille, France.
Tony LefebvreUniversité de Lille, CNRS, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, F-59000 Lille, France.
Centre National de la Recherche Scientifique · FRCentre Hospitalier Universitaire Amiens-Picardie · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRUnité de Glycobiologie Structurale et Fonctionnelle · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor occurrence and development are closely related to metabolism abnormalities. One of the metabolic networks that is dysregulated during carcinogenesis is the fatty acid synthesis pathway, which is mainly controlled by fatty acid synthase (FASN). We previously demonstrated in proliferating HepG2 liver cancer cells that FASN expression depends on the catalytic activity of

Indexed as

fatty acid synthaseliver cancermTOR pathwayO-GlcNAc transferaseO-GlcNAcylation

Identifiers

PMID35242233
PMCPMC8848257
OpenAlexW4210840189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.