Evidence map›Paper›PMID 35242184›Full record

ArticleInternational journal of endocrinology2022

Hysterosalpingography with Oil-Soluble Contrast Medium Does Not Increase Newborn Hypothyroidism.

Divya M Mathews, Jane M Peart, Neil P Johnson, Robert G Sim, Natasha L Heather, Dianne Webster, Susannah O'Sullivan, Paul L Hofman

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Divya M MathewsLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-5163-1588
Jane M PeartAuckland Radiology Group, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-2481-0134
Neil P JohnsonRepromed Auckland, Auckland, New Zealand.
Robert G SimAuckland Radiology Group, Auckland, New Zealand.
Natasha L HeatherLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0003-2895-3279
Dianne WebsterLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0003-4518-0626
Susannah O'SullivanEndocrinology, Greenlane Clinical Centre, Auckland District Health Board, Auckland, New Zealand.
Paul L HofmanLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-8995-8711
University of Auckland · NZGreenlane Clinical Centre · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHysterosalpingography (HSG) with oil-soluble contrast medium (OSCM) improves pregnancy rates in women with idiopathic infertility. However, OSCM has high iodine content and slow clearance resulting in potential iodine excess. If pregnancy occurs, this could impact fetal thyroid gland development and function. We aim to determine the effect of a preconceptional OSCM HSG on the thyroid function of the neonate.

resultsOf 146 babies included, all had normal TSH levels with values ranging from 1 to 7 mIU/L on the whole blood analysis of a capillary heel sample using the Perkin-Elmer AutoDelfia assay. Conception during the first 3 cycles following an OSCM HSG was 76%; however, TSH levels in this group were not higher than those conceived in later cycles.

conclusionPreconceptional OSCM HSG did not increase the risk of congenital hypothyroidism in the New Zealand scenario.

Identifiers

PMID35242184
PMCPMC8888087
OpenAlexW4213238415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.