Evidence map›Paper›PMID 35242146›Full record

ArticleFrontiers in immunology2022

A First for Human Vaccinology: GMP Compliant Radiation Attenuation of

Eric R James, Steve Matheny, James Overby, B Kim Lee Sim, Abraham G Eappen, Tao Li, Ming Lin Li, Thomas L Richie, Sumana Chakravarty, Anusha Gunasekera and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Eric R JamesSanaria Inc., Rockville, MD, United States.
Steve MathenySanaria Inc., Rockville, MD, United States.
James OverbySanaria Inc., Rockville, MD, United States.
B Kim Lee SimSanaria Inc., Rockville, MD, United States.
Abraham G EappenSanaria Inc., Rockville, MD, United States.
Tao LiSanaria Inc., Rockville, MD, United States.
Ming Lin LiSanaria Inc., Rockville, MD, United States.
Thomas L RichieSanaria Inc., Rockville, MD, United States.
Sumana ChakravartySanaria Inc., Rockville, MD, United States.
Anusha GunasekeraSanaria Inc., Rockville, MD, United States.
Tooba MurshedkarSanaria Inc., Rockville, MD, United States.
Peter F BillingsleySanaria Inc., Rockville, MD, United States.
Stephen L HoffmanSanaria Inc., Rockville, MD, United States.
Sanaria · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionizing radiation (UV, X-ray and ɣ) administered at an appropriate dose to pathogenic organisms can prevent replication while preserving metabolic activity. We have established the GMP process for attenuation by ionizing radiation of the

Indexed as

CulicidaeMalariaMalaria, FalciparumMalaria VaccinesAnimalsHumansPlasmodium falciparumSporozoitesVaccines, AttenuatedVaccinologyMalaria VaccinesVaccines, Attenuatedattenuationmalariaradiationsporozoitevaccine

Identifiers

PMID35242146
PMCPMC8886114
OpenAlexW4226312332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.