Evidence map›Paper›PMID 35242116›Full record

ArticleFrontiers in microbiology2022

The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in

Philip Eisenberg, Leon Albert, Jonathan Teuffel, Eric Zitzow, Claudia Michaelis, Jane Jarick, Clemens Sehlke, Lisa Große, Nicole Bader, Ariane Nunes-Alves and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Glyceraldehyde-3-phosphate dehydrogenase homologs as bifunctional gatekeepers of metabolic segregation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Streptococcus pneumoniae GAPN is a key metabolic player necessary for host infection.Protein science : a publication of the Protein Society · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Philip EisenbergInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Leon AlbertRudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
Jonathan TeuffelMolecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Eric ZitzowInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Claudia MichaelisInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Jane JarickInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Clemens SehlkeInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Lisa GroßeInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Nicole BaderRudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
Ariane Nunes-AlvesMolecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Bernd KreikemeyerInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Hermann SchindelinRudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany.
Rebecca C WadeMolecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.
Tomas FiedlerInstitute of Medical Microbiology, Virology, and Hygiene, Rostock University Medical Centre, Rostock, Germany.
University of Rostock · DEHeidelberg Institute for Theoretical Studies · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The strict human pathogen

Indexed as

computational dockingdrug targetGapNhomology modelingNADPHPNA (peptide nucleic acid)Streptococcus pyogenesX-ray crystallography

Identifiers

PMID35242116
PMCPMC8886048
OpenAlexW4226225274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.