SynthesisFrontiers in psychiatry2022
Quality of Life in Mothers With Perinatal Depression: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Effect of Bright Light Therapy on Perinatal Depression: A Systematic Review and Meta-Analysis: Effet de la luminothérapie sur la dépression périnatale: une revue systématique et une méta-analyse.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2024Pooled it
- Effectiveness of cognitive behavioural therapy-based interventions for maternal perinatal depression: a systematic review and meta-analysis.BMC psychiatry · 2023Pooled it
- Digital Mindfulness Intervention for Pregnant Women With Affective Disorders and Acute Stress Reactions: Prespecified Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Improving Maternal Mental Health and Weight Control With a Mindfulness Blended Care Approach: Insights From a Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Leveraging Machine Learning to Uncover Ethnic-Specific Predictors of Maternal Postpartum Depression.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Postpartum depression and quality of life in the first year after childbirth: ethnic differences.Social psychiatry and psychiatric epidemiology · 2026Article
- Obstetric anesthesia and postpartum mental health: implications from delivery to long-term recovery.Anesthesia and pain medicine · 2026Review
- Perinatal mood and anxiety diagnoses and treatment increased among medicaid births, 2017-2021.Scientific reports · 2026Article
- Patient perspectives on barriers to rTMS for peripartum depression.BMC psychiatry · 2026Article
- Identification, Prevention, and Treatment of Perinatal Depression in Low- and Middle-Income Countries: A Narrative Review.Biological psychiatry · 2026Review
- Perinatal Mood Disorders in Polish Women: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Health care across the first year postpartum and experiences of women with anxiety/depressive symptoms: A longitudinal cohort of first-time mothers in Ireland (MAMMI).Archives of women's mental health · 2026Article
- Strategies for spreading, scaling and sustaining perinatal mental health interventions in low- and middle-income countries (LMICs): A scoping review and thematic synthesis.Global mental health (Cambridge, England) · 2026Review
- How pre-pregnancy body mass index influences health-related quality of life during pregnancy: a serial multiple mediation analysis.BMC pregnancy and childbirth · 2025Article
- Experiences of early parenthood in and beyond the coronavirus pandemic: a qualitative study with expectant and new mothers.BMC health services research · 2025Article
- Experiences of intimate partner violence and antepartum depression among women seeking antenatal care in Addis Ababa, Ethiopia: findings from the MISPOD study.Scientific reports · 2025Article
- Home visiting for postpartum depression.The Cochrane database of systematic reviews · 2025Article
- Dropping out of a peripartum depression mHealth study: participants' motives and suggestions for improvement.BMC medical research methodology · 2025Article
- Article
- Maternal depressive symptoms trajectories and harsh parenting: the mediating role of maternal quality of life in the 2004 Pelotas Birth Cohort.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of perinatal depression is high and its adverse effects on mothers and infants are extensive. Several studies have explored the relationship between perinatal depression and health-related quality of life (HRQoL), but little is known about the nature and magnitude of this effect. The objectives of this study were to evaluate the HRQoL of mothers with perinatal depression and compare the HRQoL of depressed mothers with that of non-depressed mothers.
methodsA systematic review was performed according to the PRISMA guidelines. PubMed, EMBASE, Scopus, PsycINFO, Web of Science, Cochrane Central Register, the China National Knowledge Infrastructure, the VIP Database, and the Wan Fang Database were searched. The retrieval time was from the establishment of the database to July 2020. A series of meta-analyses were run for each outcome pertaining to HRQoL sub-measures. Subgroup analyses were conducted based on country income category and time period.
resultsOf 7,945 studies identified, 12 articles were included in the meta-analysis, providing HRQoL data for 4,392 mothers. Compared with non-depressed mothers, mothers with perinatal depression reported significantly poor scores across all the quality-of-life domains. Mixed-effects analysis showed that there was no difference in the HRQoL scores of mothers with antepartum and postpartum depression. Mothers with perinatal depression in higher-income countries reported higher disability on role-physical ( LIMITATIONS: Due to insufficient data, no regression analysis was performed. The inability to accurately determine the difference in HRQoL between antepartum and postpartum depression was because of the restriction of the included studies. Moreover, most of the included studies were conducted in middle-income countries and may have an impact on the applicability of the results. Subgroup analyses are observational and not based on random comparisons. The results of subgroup analyses should be interpreted with caution.
conclusionHRQoL is compromised in mothers with perinatal depression. Continuous efforts are required to improve the HRQoL of perinatal depressed mothers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.