Evidence map›Paper›PMID 35242028›Full record

ReviewFrontiers in pharmacology2021

Progress in the Mechanism of Autophagy and Traditional Chinese Medicine Herb Involved in Dementia.

Pengyu Tao, Jing Ji, Simeng Gu, Qian Wang, Yuzhen Xu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Pengyu TaoBasic Medical School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jing JiDepartment of Nephrology, Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Simeng GuDepartment of Psychology, Jiangsu University Medical School, Zhenjiang, China.
Qian WangPostdoctoral Workstation, Department of Central Laboratory, Taian City Central Hospital, Shandong First Medical University and Shandong Academy of Medical Sciences, Taian, China.
Yuzhen XuDepartment of Rehabilitation, The Second Affiliated Hospital of Shandong First Medical University, Taian, China.
Shanghai University of Traditional Chinese Medicine · CNAffiliated Hospital of Taishan Medical University · CNJiangsu University · CNShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dementias is a kind of neurodegenerative disease, which occurs among the aging population. Current therapeutic outcome for dementia is limited. The medical use of herbal plant has a rich history in traditional Chinese medicine practice for thousands of years. Herbal medicine (HM) may provide a positive effect for prevention and treatment in dementia. As an alternative treatment to dementia, there has been a growing interest in HM extracts in scientific community as a result of its promising study results, mainly in animal experiment. At the molecular level, HM extracts trigger autophagy and reduce generation of reactive oxygen species (ROS) while inhibiting inflammation and reduce neurotoxicity. Experiments both

Indexed as

apoptosisautophagyChinese herbal medicine extractsdementiainflammationoxidative stress

Identifiers

PMID35242028
PMCPMC8886436
OpenAlexW4213179851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.