Evidence map›Paper›PMID 35241802›Full record

ArticleNature neuroscience2022

Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling.

Yan Xiao, Luigi Petrucco, Laura J Hoodless, Ruben Portugues, Tim Czopka

Open access · hybridAbstract read
In one paragraph

Article in Nature neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 97 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Yan XiaoInstitute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany.
Luigi PetruccoMax Planck Institute of Neurobiology, Sensorimotor Control Research Group, Martinsried, Germany.ORCID http://orcid.org/0000-0003-4001-0564
Laura J HoodlessCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Ruben PortuguesMax Planck Institute of Neurobiology, Sensorimotor Control Research Group, Martinsried, Germany.ORCID http://orcid.org/0000-0002-1495-9314
Tim CzopkaInstitute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany. tim.czopka@ed.ac.uk.ORCID http://orcid.org/0000-0002-6824-8112
Munich Cluster for Systems Neurology · DEMax Planck Institute of Neurobiology · DETechnical University of Munich · DEUniversity of Edinburgh · GB

Funding

European Research Council 714440
6 · The paper itself

Abstract

Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell population. The zebrafish optic tectum contains OPCs in regions devoid of myelin. Elimination of these OPCs impaired precise control of retinal ganglion cell axon arbor size during formation and maturation of retinotectal connectivity and degraded functional processing of visual stimuli. Therefore, OPCs fine-tune neural circuits independently of their canonical role to make myelin.

Indexed as

Oligodendrocyte Precursor CellsAnimalsAxonsCell DifferentiationMyelin SheathOligodendrogliaSuperior ColliculiZebrafish

Identifiers

PMID35241802
PMCPMC8904260
OpenAlexW4220695862

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.