Evidence map›Paper›PMID 35241717›Full record

ArticleScientific reports2022

Maturation of the internal auditory canal and posterior petrous bone with relevance to lateral and posterolateral skull base approaches.

Robert C Rennert, Michael G Brandel, Jeffrey A Steinberg, Rick A Friedman, William T Couldwell, Takanori Fukushima, John D Day, Alexander A Khalessi, Michael L Levy

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparison of Inner Ear Volume Between Humans and Sheep Using MRI.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Article
  6. Article
  7. Internal auditory canal volume in normal and malformed inner ears.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Robert C RennertDepartment of Neurological Surgery, University of California, San Diego, La Jolla, CA, USA.
Michael G BrandelDepartment of Neurological Surgery, University of California, San Diego, La Jolla, CA, USA.
Jeffrey A SteinbergDepartment of Neurological Surgery, University of California, San Diego, La Jolla, CA, USA.
Rick A FriedmanDivision of Otolaryngology, Head and Neck Surgery, Department of Surgery, University of California - San Diego, La Jolla, CA, USA.
William T CouldwellDepartment of Neurosurgery, University of Utah, Salt Lake City, UT, USA.
Takanori FukushimaCarolina Neuroscience Institute, Raleigh, NC, USA.
John D DayDepartment of Neurosurgery, University of Arkansas, Little Rock, AR, USA.
Alexander A KhalessiDepartment of Neurological Surgery, University of California, San Diego, La Jolla, CA, USA.
Michael L LevyDepartment of Neurosciences and Pediatrics, University of California San Diego, San Diego, CA, USA. mlevy@rchsd.org.
Neurological Surgery · USUniversity of California, San Diego · USNeurosciences Institute · USUniversity of Arkansas at Little Rock · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anatomic knowledge of the internal auditory canal (IAC) and surrounding structures is a prerequisite for performing skull base approaches to the IAC. We herein perform a morphometric analysis of the IAC and surgically relevant aspects of the posterior petrous bone during pediatric maturation, a region well-studied in adults but not children. Measurements of IAC length (IAC-L), porus (IAC-D) and midpoint (IAC-DM) diameter, and distance from the porus to the common crus (CC; P-CC) and posterior petrosal surface (PPS) to the posterior semicircular canal (PSC; PPS-PSC) were made on thin-cut axial CT scans from 60 patients (grouped by ages 0-3, 4-7, 8-11 12-15, 16-18, and > 18 years). IAC-L increased 27.5% from 8.7 ± 1.1 at age 0-3 to 11.1 ± 1.1 mm at adulthood (p = 0.001), with the majority of growth occurring by ages 8-11. IAC-D (p = 0.52) and IAC-DM (p = 0.167) did not significantly change from ages 0-3 to adult. P-CC increased 31.1% from 7.7 ± 1.5 at age 0-3 to 10.1 ± 1.5 mm at adulthood (p = 0.019). PPS-PSC increased 160% from 1.5 ± 0.7 at age 0-3 to 3.9 ± 1.2 mm at adulthood (p < 0.001). The majority of growth in P-CC and PPS-PSC occurred by ages 12-15. Knowledge of these patterns may facilitate safe exposure of the IAC in children.

Indexed as

Petrous BoneSkull BaseAdolescentAdultChildChild, PreschoolHumansInfantInfant, NewbornSemicircular CanalsTomography, X-Ray Computed

Identifiers

PMID35241717
PMCPMC8894491
OpenAlexW4214819691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.