Evidence map›Paper›PMID 35241695›Full record

ArticleScientific reports2022

An innovative green synthesis approach of chitosan nanoparticles and their inhibitory activity against phytopathogenic Botrytis cinerea on strawberry leaves.

Noura El-Ahmady El-Naggar, WesamEldin I A Saber, Amal M Zweil, Shimaa I Bashir

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
7.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 109 citations in OpenAlex.

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  16. Chitosan Nanoparticle-EncapsulatedInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Noura El-Ahmady El-NaggarDepartment of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt. nouraalahmady@yahoo.com.ORCID http://orcid.org/0000-0001-8493-9194
WesamEldin I A SaberMicrobial Activity Unit, Department of Microbiology, Soils, Water and Environment Research Institute, Agricultural Research Center, Giza, 12619, Egypt.ORCID https://orcid.org/0000-0003-0631-4089
Amal M ZweilPlant Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.
Shimaa I BashirDepartment of Plant Protection and Biomolecular Diagnosis, Arid Land Cultivation Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt.
City of Scientific Research and Technological Applications · EGAgricultural Research Center · EGUniversity of Sadat City · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Green synthesis is a newly emerging field of nanobiotechnology that offers economic and environmental advantages over traditional chemical and physical protocols. Nontoxic, eco-friendly, and biosafe materials are used to implement sustainable processes. The current work proposes a new biological-based strategy for the biosynthesis of chitosan nanoparticles (CNPs) using Pelargonium graveolens leaves extract. The bioconversion process of CNPs was maximized using the response surface methodology. The best combination of the tested parameters that maximized the biosynthesis process was the incubation of plant extract with 1.08% chitosan at 50.38 °C for 57.53 min., yielding 9.82 ± 3 mg CNPs/mL. Investigation of CNPs by SEM, TEM, EDXS, zeta potential, FTIR, XRD, TGA, and DSC proved the bioconversion process's success. Furthermore, the antifungal activity of the biosynthesized CNPs was screened against a severe isolate of the phytopathogenic Botrytis cinerea. CNPs exerted efficient activity against the fungal growth. On strawberry leaves, 25 mg CNPs/mL reduced the symptoms of gray mold severity down to 3%. The higher concentration of CNPs (50 mg/mL) was found to have a reverse effect on the infected area compared with those of lower concentrations (12.5 and 25 mg CNPs/mL). Therefore, additional work is encouraged to reduce the harmful side effects of elevated CNPs concentrations.

Indexed as

ChitosanFragariaNanoparticlesBotrytisPlant LeavesChitosan

Identifiers

PMID35241695
PMCPMC8894456
OpenAlexW4214825545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.