Evidence map›Paper›PMID 35241689›Full record

ArticleScientific reports2022

Changes in the excitability of primary hippocampal neurons following exposure to 3.0 GHz radiofrequency electromagnetic fields.

Ibtissam Echchgadda, Jody C Cantu, Gleb P Tolstykh, Joseph W Butterworth, Jason A Payne, Bennett L Ibey

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Pilot Study of the Long-Term Effects of Radiofrequency Electromagnetic Radiation Exposure on the Mouse Brain.International journal of environmental research and public health · 2023
    Article
  6. Frontiers in public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ibtissam EchchgaddaAir Force Research Laboratory, 711Th Human Performance Wing, Airman Systems Directorate, Bioeffects Division, Radio Frequency Bioeffects Branch, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA. ibtissam.echchgadda.1@us.af.mil.
Jody C CantuGeneral Dynamics Information Technology, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA.
Gleb P TolstykhGeneral Dynamics Information Technology, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA.
Joseph W ButterworthGeneral Dynamics Information Technology, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA.
Jason A PayneAir Force Research Laboratory, 711Th Human Performance Wing, Airman Systems Directorate, Bioeffects Division, Radio Frequency Bioeffects Branch, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA.
Bennett L IbeyAir Force Research Laboratory, 711Th Human Performance Wing, Airman Systems Directorate, Bioeffects Division, Radio Frequency Bioeffects Branch, JBSA Fort Sam Houston, 4141 Petroleum Road, San Antonio, TX, 78234, USA.
General Dynamics (United States) · US711th Human Performance Wing59th Medical Wing · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposures to radiofrequency electromagnetic fields (RF-EMFs, 100 kHz to 6 GHz) have been associated with both positive and negative effects on cognitive behavior. To elucidate the mechanism of RF-EMF interaction, a few studies have examined its impact on neuronal activity and synaptic plasticity. However, there is still a need for additional basic research that further our understanding of the underlying mechanisms of RF-EMFs on the neuronal system. The present study investigated changes in neuronal activity and synaptic transmission following a 60-min exposure to 3.0 GHz RF-EMF at a low dose (specific absorption rate (SAR) < 1 W/kg). We showed that RF-EMF exposure decreased the amplitude of action potential (AP), depolarized neuronal resting membrane potential (MP), and increased neuronal excitability and synaptic transmission in cultured primary hippocampal neurons (PHNs). The results show that RF-EMF exposure can alter neuronal activity and highlight that more investigations should be performed to fully explore the RF-EMF effects and mechanisms.

Indexed as

Electromagnetic FieldsHippocampusNeuronsRadio Waves

Identifiers

PMID35241689
PMCPMC8894459
OpenAlexW4220947175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.