Evidence map›Paper›PMID 35241683›Full record

ArticleScientific reports2022

Federated learning for multi-center imaging diagnostics: a simulation study in cardiovascular disease.

Akis Linardos, Kaisar Kushibar, Sean Walsh, Polyxeni Gkontra, Karim Lekadir

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akis LinardosDepartment of Mathematics and Computer Science, University of Barcelona, 08007, Barcelona, Spain. linardos.akis@ub.edu.
Kaisar KushibarDepartment of Mathematics and Computer Science, University of Barcelona, 08007, Barcelona, Spain.
Sean WalshRadiomics, 4000, Liège, Belgium.
Polyxeni GkontraDepartment of Mathematics and Computer Science, University of Barcelona, 08007, Barcelona, Spain.
Karim LekadirDepartment of Mathematics and Computer Science, University of Barcelona, 08007, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center datasets, and although some results have shown promise, their generalizability to other institutions remains questionable as the data heterogeneity between institutions is not taken into account. By allowing models to be trained in a distributed manner that preserves patients' privacy, federated learning promises to alleviate these issues, by enabling diligent multi-center studies. We present the first simulated federated learning study on the modality of cardiovascular magnetic resonance and use four centers derived from subsets of the M&M and ACDC datasets, focusing on the diagnosis of hypertrophic cardiomyopathy. We adapt a 3D-CNN network pretrained on action recognition and explore two different ways of incorporating shape prior information to the model, and four different data augmentation set-ups, systematically analyzing their impact on the different collaborative learning choices. We show that despite the small size of data (180 subjects derived from four centers), the privacy preserving federated learning achieves promising results that are competitive with traditional centralized learning. We further find that federatively trained models exhibit increased robustness and are more sensitive to domain shift effects.

Indexed as

Cardiovascular DiseasesComputer SimulationConfidentialityHumansMagnetic Resonance ImagingPrivacy

Identifiers

PMID35241683
PMCPMC8894335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.