Evidence map›Paper›PMID 35241481›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Differential Diagnosis of Parkinsonism Based on Deep Metabolic Imaging Indices.

Ping Wu, Yu Zhao, Jianjun Wu, Matthias Brendel, Jiaying Lu, Jingjie Ge, Alexander Bernhardt, Ling Li, Ian Alberts, Sabrina Katzdobler and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Machine Learning Models of Voxel-Level [Annals of neurology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Cross-modality PET image synthesis for Parkinson's Disease diagnosis: a leap from [European journal of nuclear medicine and molecular imaging · 2025
    Article
  12. Article
  13. Article
  14. Application of Artificial Intelligence in Nuclear Neuroimaging.Nuclear medicine and molecular imaging · 2024
    Article
  15. Article
  16. Article
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  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 3 countries.

Ping WuPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Yu ZhaoDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Jianjun WuDepartment of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Matthias BrendelDepartment of Nuclear Medicine, University of Munich, Munich, Germany.
Jiaying LuPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Jingjie GePET Center, Huashan Hospital, Fudan University, Shanghai, China.
Alexander BernhardtDepartment of Neurology, University of Munich, Munich, Germany.
Ling LiPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Ian AlbertsDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Sabrina KatzdoblerDepartment of Neurology, University of Munich, Munich, Germany.
Igor YakushevDepartment of Nuclear Medicine, Technische Universität München, Munich, Germany.
Jimin HongDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Qian XuPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Yimin SunNational Research Center for Aging and Medicine & National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China.
Fengtao LiuNational Research Center for Aging and Medicine & National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China.
Johannes LevinDepartment of Neurology, University of Munich, Munich, Germany.
Günter U HöglingerDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Claudio BassettiDepartment of Neurology, University of Bern, Bern, Switzerland; and.
Yihui GuanPET Center, Huashan Hospital, Fudan University, Shanghai, China.
Wolfgang H OertelDepartment of Neurology, University of Marburg, Marburg, Germany.
Wolfgang WeberDepartment of Nuclear Medicine, Technische Universität München, Munich, Germany.
Axel RomingerDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Jian WangNational Research Center for Aging and Medicine & National Center for Neurological Disorders, Huashan Hospital, Fudan University, Shanghai, China; zuochuantao@fudan.edu.cn wangjian_hs@fudan.edu.cn.
Chuantao ZuoPET Center, Huashan Hospital, Fudan University, Shanghai, China; zuochuantao@fudan.edu.cn wangjian_hs@fudan.edu.cn.
Kuangyu ShiDepartment of Nuclear Medicine, University of Bern, Bern, Switzerland.
Huashan Hospital · CNUniversity of Bern · CHLudwig-Maximilians-Universität München · DEFudan University · CNTechnical University of Munich · DEMedizinische Hochschule Hannover · DEPhilipps University of Marburg · DETencent (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical presentations of early idiopathic Parkinson disease (IPD) substantially overlap with those of atypical parkinsonian syndromes such as multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). This study aimed to develop metabolic imaging indices based on deep learning to support the differential diagnosis of these conditions.

Indexed as

Multiple System AtrophyParkinson DiseaseParkinsonian DisordersSupranuclear Palsy, ProgressiveArtificial IntelligenceDiagnosis, DifferentialHumansatypical parkinsonian syndromedeep learningdeep metabolic imaging indicesdifferential diagnosisParkinson disease

Identifiers

PMID35241481
PMCPMC9635684
OpenAlexW4214882083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.