Evidence map›Paper›PMID 35241443›Full record

Observational studyThe British journal of ophthalmology2023

Application of mydriasis and eye steering in ultrawide field imaging for detecting peripheral retinal lesions in myopic patients.

Meiyan Li, Danjuan Yang, Yang Shen, Jianmin Shang, Lingling Niu, Yongfu Yu, Xiaoying Wang, Peijun Yao, Xingtao Zhou

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in The British journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. IMI-Instrumentation for Myopia Management.Investigative ophthalmology & visual science · 2025
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Meiyan Li *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Danjuan Yang *Eye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Yang ShenEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Jianmin ShangEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Lingling NiuEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.
Yongfu YuDepartment of Biostatistics, School of Public Health of Fudan University, Shanghai, China.
Xiaoying WangEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-5419-6318
Peijun YaoEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China doctzhouxingtao@163.com pjyao@hotmail.com.
Xingtao ZhouEye Institute and Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China doctzhouxingtao@163.com pjyao@hotmail.com.ORCID http://orcid.org/0000-0002-3465-1579
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare mydriatic and eye-steering ultrawide field imaging (UWFI) with standard non-mydriatic UWFI examination in detecting peripheral retinal lesions in myopic patients.

methodsCross-sectional, observational study. 220 eyes of 110 myopic patients with known peripheral retinal lesions in at least one eye under Goldmann three mirror contact lens examination were recruited. Non-mydriatic standard and eye-steering UWFI images were taken centrally and with eye-steering technique in upper, lower, nasal and temporal gazes under Optomap UWFI (Daytona, Optos, UK). Mydriatic standard and eye-steering UWFI was captured in central gaze and four different peripheral gazes. Sensitivity of detecting peripheral retinal lesions under different UWFI settings was compared.

results141 (64.09%) eyes were with peripheral retinal lesions. The sensitivity for detecting peripheral lesions from low to high was 41.84% (95% CI 33.62% to 50.54%) under non-mydriatic standard UWFI setting, 52.48% (95% CI 44.08% to 60.75%) under mydriatic standard setting, 75.18% (95% CI 67.21% to 82.06%) under non-mydriatic eye-steering setting and 86.52% (95% CI 79.76% to 91.69%) under mydriatic eye-steering setting. Both mydriasis and eye-steering technique increased sensitivity of detecting peripheral lesions with statistical significance (p<0.001). By applying eye-steering technique, sensitivity of detecting lesions located in superior and inferior quadrants witnessed a greater increase compared with other two quadrants (p<0.05). Neither spherical equivalence (p>0.05) nor axial length (p>0.05) was an independent influence factor for detecting peripheral lesions.

conclusionsEye-steering technique and mydriasis could both efficiently improve the sensitivity of detecting peripheral retinal lesions in myopic patients. Lesions of superior and inferior quadrants benefited more from eye-steering technique.

Indexed as

MydriasisMyopiaCross-Sectional StudiesDiagnostic ImagingEyeHumansMydriaticsMydriaticsdiagnostic tests/investigationimaging

Identifiers

PMID35241443
PMCPMC10359684
OpenAlexW4214948653

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.